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Chemical Structure| 2216-69-5

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Product Details of 1-Methoxynaphthalene

CAS No. :2216-69-5
Formula : C11H10O
M.W : 158.20
SMILES Code : COC1=C2C=CC=CC2=CC=C1
MDL No. :MFCD00003924

Safety of 1-Methoxynaphthalene

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 1-Methoxynaphthalene

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 2216-69-5 ]
  • Downstream synthetic route of [ 2216-69-5 ]

[ 2216-69-5 ] Synthesis Path-Upstream   1~4

  • 1
  • [ 108-30-5 ]
  • [ 2216-69-5 ]
  • [ 3562-99-0 ]
YieldReaction ConditionsOperation in experiment
86.4% With aluminum (III) chloride In dichloromethane at 33 - 37℃; for 6 h; 15.8 g of 1-methoxynaphthalene and 10.0 g of succinic anhydride were dissolved in 120 mL of dichloromethane,Stir,Cooling to 1 ~ 3 ° C,Divided into three batches of anhydrous aluminum trichloride 15.0 grams,The addition process takes about 20 minutes,The solution was then heated to 35 ± 2 ° C,Insulation reaction 6 hours (5.5 ~ 6.5 hours range),After the reaction is complete,The reaction solution was poured into an ice-water mixture (200 g of ice and 300 g of water) for 30 minutes,Standing, analysiscrystal,Filter,The filtrate was heated and distilled to recover dichloromethane,The cake is the crude of the ketone ketone;And then the crude ketoprofen water as a solvent by 2-3 times recrystallization,Activated carbon decolorization,Demon ketone boutique.The mass of the present product of the chamballone was 22.3 g,Melting point of 176 ~ 179 ° C,The yield was 86.4percent.
References: [1] Patent: CN104370734, 2016, B, . Location in patent: Paragraph 0016-0018.
[2] Helvetica Chimica Acta, 1932, vol. 15, p. 907,914.
[3] Journal of the University of Bombay, Science: Physical Sciences, Mathematics, Biological Sciences and Medicine, 1936, vol. 5/2, p. 73,75.
[4] Journal of the American Chemical Society, 1940, vol. 62, p. 2750,2752.
[5] Journal of the American Chemical Society, 1951, vol. 73, p. 897,899.
[6] Journal of the American Chemical Society, 1951, vol. 73, p. 326,327.
[7] Kogyo Kagaku Zasshi, 1953, vol. 56, p. 887,889[8] Chem.Abstr., 1955, p. 6904.
[9] Journal of the American Chemical Society, 1936, vol. 58, p. 2314,2316.
[10] Bulletin de la Societe Chimique de France, 1968, p. 627 - 631.
[11] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 285.
  • 2
  • [ 108-30-5 ]
  • [ 75-15-0 ]
  • [ 7446-70-0 ]
  • [ 2216-69-5 ]
  • [ 3562-99-0 ]
References: [1] Journal of the American Chemical Society, 1936, vol. 58, p. 2314,2316.
[2] Helvetica Chimica Acta, 1932, vol. 15, p. 907,914.
[3] Journal of the University of Bombay, Science: Physical Sciences, Mathematics, Biological Sciences and Medicine, 1936, vol. 5/2, p. 73,75.
  • 3
  • [ 108-30-5 ]
  • [ 7446-70-0 ]
  • [ 630-20-6 ]
  • [ 2216-69-5 ]
  • [ 3562-99-0 ]
References: [1] Journal of the American Chemical Society, 1936, vol. 58, p. 2314,2316.
[2] Helvetica Chimica Acta, 1932, vol. 15, p. 907,914.
[3] Journal of the University of Bombay, Science: Physical Sciences, Mathematics, Biological Sciences and Medicine, 1936, vol. 5/2, p. 73,75.
  • 4
  • [ 108-30-5 ]
  • [ 7446-70-0 ]
  • [ 98-95-3 ]
  • [ 2216-69-5 ]
  • [ 3562-99-0 ]
References: [1] Journal of the American Chemical Society, 1936, vol. 58, p. 2314,2316.
[2] Helvetica Chimica Acta, 1932, vol. 15, p. 907,914.
[3] Journal of the University of Bombay, Science: Physical Sciences, Mathematics, Biological Sciences and Medicine, 1936, vol. 5/2, p. 73,75.
 

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