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Chemical Structure| 1010802-72-8 Chemical Structure| 1010802-72-8

Structure of 1010802-72-8

Chemical Structure| 1010802-72-8

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Product Details of [ 1010802-72-8 ]

CAS No. :1010802-72-8
Formula : C5H6BrClO
M.W : 197.46
SMILES Code : O=C(Cl)C(Br)C1CC1
MDL No. :MFCD20482404

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Application In Synthesis of [ 1010802-72-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1010802-72-8 ]

[ 1010802-72-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1010802-72-8 ]
  • [ 64-17-5 ]
  • [ 1200828-74-5 ]
YieldReaction ConditionsOperation in experiment
at 20℃; for 1h; Absolute ethanol (200 mL) was added and the resulting dark brown solution was stirred at room temperature for one hour. The reaction mixture was concentrated under reduced pressure, and the residue was suspended in carbon tetrachloride (300 mL) and filtered through a glass filter. The filtrate was concentrated under the reduced pressure. The resulting product was purified by flash chromatography (silica gel, two 330 g columns, eluent: 5% ethyl acetate in hexanes) to provide racemic ethyl 2-bromo-2- cyclopropylacetate. 1H NMR (400 MHz, CDCl3, delta, ppm): 4.24 (m, 2H), 3.58 (d, J=12.0 Hz, 1H), 1.58 (m, 1H), 0.90-0.80 (m, 2H), 0.53 (m, 1H), 0.42 (m, 1H), 1.3 (t, j = 8.0 Hz, 3H).
 

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