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Chemical Structure| 101420-96-6 Chemical Structure| 101420-96-6

Structure of 101420-96-6

Chemical Structure| 101420-96-6

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Product Details of [ 101420-96-6 ]

CAS No. :101420-96-6
Formula : C7H4ClN3O2
M.W : 197.58
SMILES Code : O=[N+](C1=C(Cl)C=CC2=C1C=NN2)[O-]

Safety of [ 101420-96-6 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 101420-96-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 101420-96-6 ]

[ 101420-96-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 219312-08-0 ]
  • [ 101420-96-6 ]
YieldReaction ConditionsOperation in experiment
To 4-chloro-2-methyl-3-nitroaniline(1.63 g, 8.8 mmol) dissolved in acetic acid (75 mL) at room temperature was added a 2M aqueous solution of sodium nitrite (4.4 mL). The suspension was then diluted with acetic acid (100 mL) and then heated at reflux for 4 h. The mixture was then cooled to room temperature and concentrated under reduced pressure. The residue was then partitioned between ethyl acetate (100 mL) and saturated aqueous sodium hydrogen carbonate solution (100 mL). The separated organic layer was then washed with brine, dried over magnesium sulfate and concentrated under reduced pressure. Column chromatography of the reside (hexane/ethyl acetate (2: 1) afforded the desired product. 1H NMR (500MHz) (DMSOd6) δ 8.32 (s, IH); 7.95 (d, J=8.7Hz, IH); 7.68 (d, J=8.7Hz, IH
 

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