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Chemical Structure| 1023334-50-0 Chemical Structure| 1023334-50-0

Structure of 1023334-50-0

Chemical Structure| 1023334-50-0

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Product Details of [ 1023334-50-0 ]

CAS No. :1023334-50-0
Formula : C7H6BrClN2O
M.W : 249.49
SMILES Code : O=C(NN)C1=CC=C(Cl)C=C1Br
MDL No. :MFCD03425669

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* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1023334-50-0 ]

[ 1023334-50-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 57381-62-1 ]
  • [ 1023334-50-0 ]
YieldReaction ConditionsOperation in experiment
56% With hydrazine hydrate; In methanol; at 60℃; for 1h; To a solution of <strong>[57381-62-1]methyl 2-bromo-4-chlorobenzoate</strong> (In-27, 5.0 g, 20.0 mmol) in MeOH (50 mL) was added N2H4.H20 (80percent, 50 mL). The resulting solution was heated at 60 °C for 1 h, until TLC show SM consumed. After concentration, the resulting solid was dissolved in EA (100 mL), washed with brine (2 x 30 mL), dried over Na2504 and concentrated to dryness to afford desired product 2-bromo-4-chlorobenzohydrazide Sc (2.8 g, 56percent). ?H NMR(300 MHz, DMSO-d6): oe 9.58 (s, 1H), 7.80 (d, J=1.8 Hz, 1H), 7.52 (dd, J8.1 Hz, J=2.1 Hz, 1H), 7.38 (d,J=8.1 Hz, 1H), 4.49 (s, 2H). LC-MS [M+Hj 251;
 

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