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Chemical Structure| 10242-15-6 Chemical Structure| 10242-15-6

Structure of 10242-15-6

Chemical Structure| 10242-15-6

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Product Details of [ 10242-15-6 ]

CAS No. :10242-15-6
Formula : C10H5NO6
M.W : 235.15
SMILES Code : O=C(C(C1=O)=CC2=C(O1)C=CC([N+]([O-])=O)=C2)O
MDL No. :MFCD00052754

Safety of [ 10242-15-6 ]

Application In Synthesis of [ 10242-15-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 10242-15-6 ]

[ 10242-15-6 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 138907-68-3 ]
  • [ 10242-15-6 ]
  • ethyl 1-(4-fluorophenyl)-5-(6-nitro-2-oxo-2H-chromene-3-carboxamido)-1H-pyrazole-4-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
70% With pyridine; trichlorophosphate; General procedure: Intermediate 4 (0.001mol) and 5 (0.001mol) were dissolved in pyridine, phosphorus oxychloride is slowly added dropwise under ice bath conditions, then at 40-60C reacted for 5-8h. Finally, the mixture was poured into 30mL saturated Na2CO3 solution and stirred well. After the mixture was acidified, the saturated CuSO4 solution was used to remove pyridine, which greatly improved the purity and yield of the product. The data for compounds 8I-8VI are provided in the supporting information.
  • 2
  • [ 10242-15-6 ]
  • [ 15001-11-3 ]
  • ethyl 5-(6-nitro-2-oxo-2H-chromene-3-carboxamido)-1-(p-tolyl)-1H-pyrazole-4-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
68% With pyridine; trichlorophosphate; General procedure: Intermediate 4 (0.001mol) and 5 (0.001mol) were dissolved in pyridine, phosphorus oxychloride is slowly added dropwise under ice bath conditions, then at 40-60C reacted for 5-8h. Finally, the mixture was poured into 30mL saturated Na2CO3 solution and stirred well. After the mixture was acidified, the saturated CuSO4 solution was used to remove pyridine, which greatly improved the purity and yield of the product. The data for compounds 8I-8VI are provided in the supporting information.
  • 3
  • [ 10242-15-6 ]
  • [ 51516-70-2 ]
  • N-(4-cyano-1-(4-fluorophenyl)-1H-pyrazol-5-yl)-6-nitro-2-oxo-2H-chromene-3-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
70% With pyridine; trichlorophosphate; General procedure: Intermediate 4 (0.001mol) and 5 (0.001mol) were dissolved in pyridine, phosphorus oxychloride is slowly added dropwise under ice bath conditions, then at 40-60C reacted for 5-8h. Finally, the mixture was poured into 30mL saturated Na2CO3 solution and stirred well. After the mixture was acidified, the saturated CuSO4 solution was used to remove pyridine, which greatly improved the purity and yield of the product. The data for compounds 8I-8VI are provided in the supporting information.
  • 4
  • [ 103646-82-8 ]
  • [ 10242-15-6 ]
  • N-(4-cyano-1-(p-tolyl)-1H-pyrazol-5-yl)-6-nitro-2-oxo-2H-chromene-3-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
70% With pyridine; trichlorophosphate; General procedure: Intermediate 4 (0.001mol) and 5 (0.001mol) were dissolved in pyridine, phosphorus oxychloride is slowly added dropwise under ice bath conditions, then at 40?60°C reacted for 5?8h. Finally, the mixture was poured into 30mL saturated Na2CO3 solution and stirred well. After the mixture was acidified, the saturated CuSO4 solution was used to remove pyridine, which greatly improved the purity and yield of the product. The data for compounds 8I-8VI are provided in the supporting information.
 

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