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Chemical Structure| 102879-75-4 Chemical Structure| 102879-75-4

Structure of 102879-75-4

Chemical Structure| 102879-75-4

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Product Details of [ 102879-75-4 ]

CAS No. :102879-75-4
Formula : C10H17N3O4
M.W : 243.26
SMILES Code : CCOC(OCC)CC1=C(N)N=C(O)N=C1O

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Application In Synthesis of [ 102879-75-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 102879-75-4 ]

[ 102879-75-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 52133-67-2 ]
  • [ 57-13-6 ]
  • [ 102879-75-4 ]
YieldReaction ConditionsOperation in experiment
40% Stepi 6-Amino-5-(2,2-diethoxyethyl)-pyrimidine-2,4-diolTo a solution of urea (5.24 g; 87.2 mmol) in anhydrous ethanol (200 ml), under a nitrogen atmosphere, was added 2-cyano-4,4-diethoxy butyric acid ethyl ester [prepared as detailed in Davoll. J. J. Chem. Soc, 1960, pp131-138] (20 g; 87.2 mmol) followed by sodium ethoxide (11.88 g; 172.6 mmol). The reaction mixture was heated at reflux overnight. The reaction was allowed to cool to ambient temperature and then water (500 ml) and acetic acid (5 ml) were added. The solution was cooled to approximately 5 0C and a pale brown solid formed which was collected by filtration (8.4 g; 40percent). LC/MS: RT = 1.37 min; m/z = 198 [M -EtOH]+. Total run time 3.75 mins <n="39"/>1H NMR (dbeta DMSO): delta 1.07 (t, 3H); 2.40 (d, 2H); 3.39 (m, 2H); 3.60 (m, 2H); 4.45 (t, 1H); 10.08 (s, 1H); 10.8 (br s, 1 H).
 

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