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Chemical Structure| 1029-52-3 Chemical Structure| 1029-52-3

Structure of 1029-52-3

Chemical Structure| 1029-52-3

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Product Details of [ 1029-52-3 ]

CAS No. :1029-52-3
Formula : C14H16N4O
M.W : 256.30
SMILES Code : O=C1C(CN(CC2=CC=CC=C2)CC3)=C3N=C(N)N1
MDL No. :MFCD09999171

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Application In Synthesis of [ 1029-52-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1029-52-3 ]

[ 1029-52-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 57611-47-9 ]
  • [ 50-01-1 ]
  • [ 1029-52-3 ]
YieldReaction ConditionsOperation in experiment
87% With potassium carbonate; In N,N-dimethyl-formamide; Synthesis of CO-AA W00014 Synthesis of pentanoic acid [6-benzyl-4-(2-chloro-phenyl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-2-yl]-amide: Methyl-1-benzyl-4-oxo-3-piperidine carboxylate (5.68g., 20mmoles) and guanidine hydrochloride (2.0g., 21mmoles) were suspended and stirred in dry DMF (45mls) before potassium carbonate (5.68g., 41mmoles) was added portionwise over 15 minutes. The reaction mixture was poured onto cold water (750mIs) to release a white/beige solid which was rapidly stirred for 30 minutes. The solid was filtered washed with water (100 mls) and dried in a vacuum desiccator. The product was then slurried in ether (150mIs), filtered and dried in vacuo overnight, to leave an off-white solid (4.46g., 87% yield). Single spot by tic (MeOH, Rf 0.66), LC-MS (retention 2.20mins., mass 257 M+H).
 

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