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Chemical Structure| 107175-49-5 Chemical Structure| 107175-49-5

Structure of 107175-49-5

Chemical Structure| 107175-49-5

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Product Details of [ 107175-49-5 ]

CAS No. :107175-49-5
Formula : C7H13I
M.W : 224.08
SMILES Code : C=CCCCCCI
MDL No. :MFCD10570159

Safety of [ 107175-49-5 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331-H341
Precautionary Statements:P201-P202-P261-P264-P270-P271-P280-P302+P352-P304+P340-P308+P313-P310-P330-P361-P403+P233-P405-P501
Class:6.1
UN#:2810
Packing Group:

Application In Synthesis of [ 107175-49-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 107175-49-5 ]

[ 107175-49-5 ] Synthesis Path-Downstream   1~2

  • 1
  • 10-[(3RS,4RS)-3-Ethyl-7-hydroxy-3-(4-hydroxyphenyl)thiochroman-4-yl]-2-(7,7,8,8,8-pentafluorooctyl)-decanoic Acid [ No CAS ]
  • [ 2043-55-2 ]
  • [ 107175-49-5 ]
  • [ 105-53-3 ]
  • 10-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)thiochroman-4-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)decanoic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
Example 31 Synthesis of 10-[(3RS,4RS)-3-Ethyl-7-hydroxy-3-(4-hydroxyphenyl)thiochroman-4-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)decanoic Acid Starting with the ethyl 2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)-8-nonenoate prepared from diethyl malonate, 7-iodo-1-heptene and <strong>[2043-55-2]1-iodo-3,3,4,4,5,5,6,6,6-nonafluorohexane</strong> as in Example 9 and the allyl compound prepared in Example 13, the same procedure as shown in Example 13 was repeated to give 10-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)thiochroman-4-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)decanoic acid. 1H-NMR (300 MHz, CDCl3): d 7.17 (d, J=9 Hz, 2H, Ar-H), 6.86 (d, J=8 Hz, 1H, Ar-H), 6.83 (d, J=9 Hz, 2H, Ar-H), 6.66 (d, J=2 Hz, 1H, Ar-H), 6.48 (dd, J=8 Hz, 2 Hz, 1H, Ar-H), 3.46 (d, J=12 Hz, 1H, C2-H), 3.08 (d, J=12 Hz, 1H, C2-H), 2.72 (br s, 1H, C4-H), 2.45 (m, 1H, CHCO2H), 2.2-2.0 (m, 2H, CH2CF2), 2.0-0.9 (m, 20H, C3-CH2CH3 and alkyl-H), 0.49 (t, 3H, J=7 Hz, 2H, C3-CH2CH3).
  • 2
  • 11-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)chroman-4-yl]-2-(7,7,8,8,8-pentafluorooctyl)-undecanoic acid [ No CAS ]
  • [ 2043-55-2 ]
  • [ 107175-49-5 ]
  • [ 105-53-3 ]
  • 10-[(3RS,4RS)-3-Ethyl-7-hydroxy-3-(4-hydroxyphenyl)chroman-4-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)-decanoic Acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
Example 33 Synthesis of 10-[(3RS,4RS)-3-Ethyl-7-hydroxy-3-(4-hydroxyphenyl)chroman-4-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)-decanoic Acid Starting with the ethyl 2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)-8-nonenoate prepared from diethyl malonate, 7-iodo-1-heptene and <strong>[2043-55-2]1-iodo-3,3,4,4,5,5,6,6,6-nonafluorohexane</strong> as in Example 9 and the allyl compound prepared in Example 21, the same procedure as shown in Example 21 was repeated to give 10-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)chroman-4-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)decanoic acid. 1H-NMR (300 MHz, CDCl3): delta 7.02 (d, 2H, J=8.7 Hz), 6.87 (d, 1H, J=7.5 Hz), 6.84 (d, 2H, J=8.7 Hz), 6.40-6.30 (m, 2H), 4.45 (d, 1H, J=10.6 Hz), 4.35 (d, 1H, J=10.6 Hz), 2.61 (bs, 1H), 2.36 (m, 1H), 2.19-0.97 (m, 22H), 0.59 (t, 3H). Mass (ESI): 687 (M+1).
 

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