Home Cart Sign in  
Chemical Structure| 1073477-74-3 Chemical Structure| 1073477-74-3

Structure of 1073477-74-3

Chemical Structure| 1073477-74-3

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1073477-74-3 ]

CAS No. :1073477-74-3
Formula : C7H4F4O2
M.W : 196.10
SMILES Code : OC1=CC=C(OC(F)(F)F)C=C1F
MDL No. :MFCD23111095
InChI Key :PFEFZNARVCCVLN-UHFFFAOYSA-N
Pubchem ID :59415115

Safety of [ 1073477-74-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 1073477-74-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1073477-74-3 ]

[ 1073477-74-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 503309-10-2 ]
  • [ 1073477-74-3 ]
YieldReaction ConditionsOperation in experiment
67% With dihydrogen peroxide; In dichloromethane; at 20℃; for 2h; To a 20 C. solution of C23 (from the previous step; 43 g, ≦193 mmol) in dichloromethane (300 mL) was added hydrogen peroxide (30% solution, 99 mL, 1.0 mol), and the reaction mixture was stirred at 20 C. for 2 hours. It was then partitioned between water (200 mL) and dichloromethane (200 mL); the aqueous layer was extracted with dichloromethane (2×100 mL), and the combined organic layers were washed with saturated aqueous sodium chloride solution (200 mL), dried over sodium sulfate, filtered, and concentrated under reduced pressure. Silica gel chromatography (Eluent: 10% ethyl acetate in petroleum ether) provided the product (30 g, which by 1H NMR analysis consisted of a 1:0.3 molar ratio of product and ethyl acetate) as a yellow oil. Corrected yield: 26 g, 130 mol, 67% over 2 steps. LCMS m/z 195.0 [M-H+]. 1H NMR (400 MHz, CDCl3), product peaks only: δ 6.98-7.05 (m, 2H), 6.94 (br d, half of AB quartet, J=9 Hz, 1H) 5.54 (br d, J=3.3 Hz, 1H).
 

Historical Records

Technical Information

Categories