[ CAS No. 1075719-87-7 ] {[proInfo.proName]}

Name: 1075719-87-7|2-(4-Ethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|98%
Brand: Ambeed
SKU: A658676
Price: 25.0 USD
Availability: InStock
Rating: 97 (28 reviews)

,{[proInfo.pro_purity]}

Cat. No.: {[proInfo.prAm]}

2D 3D

Structure of 1075719-87-7 * Storage: {[proInfo.prStorage]}

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

For Research Only 110K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 1075719-87-7 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 1075719-87-7 ]

SDS Specification

Alternatived Products of [ 1075719-87-7 ]

Product Details of [ 1075719-87-7 ]

CAS No. :	1075719-87-7	MDL No. :	MFCD18643353
Formula :	C₁₄H₂₁BO₂	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	RWANCHDMVNWYHW-UHFFFAOYSA-N
M.W :	232.13	Pubchem ID :	59788424
Synonyms :

Safety of [ 1075719-87-7 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P261-P305+P351+P338	UN#:	N/A
Hazard Statements:	H302-H315-H319-H335	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 1075719-87-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 1075719-87-7 ]

[ 1075719-87-7 ] Synthesis Path-Downstream 1~33

1
[ 25309-64-2 ]
[ 25015-63-8 ]
[ 1075719-87-7 ]

Yield	Reaction Conditions	Operation in experiment
96%	With magnesium; triethylamine; In tetrahydrofuran; for 15h;Reflux;	Example 1Preparation of pinacol ester of 4-ethylphenylboronic acid In a 2 necks Schlenk type flask, provided with a magnetic stirring bar and topped by a coolant, 4-ethylbenzene iodide (0.232 g, 1 mmol), pinacolborane (0.128 g, 1 mmol) and triethylamine (59 mg, 1 mmol) are added to 10 ml of a distilled THF solution containing magnesium turnings (24 mg, 1 mmol). The reactive mixture is stirred for approximately 15 hours at THF reflux.At the end of the reaction, the crude reaction product is hydrolyzed by 20 ml of neutral water and extracted by diethyl ether (3×40 ml). The joined organic phases are washed by 2×50 ml of neutral water then dried on MgSO4. After solvent evaporation, the obtained yield is of 96% with a total conversion of the starting iodide (yield/conversion of 96%). The resulting boronic ester is analyzed by GC, NMR 1H and 13C and GC/MS.Characterizations:NMR 1H, 7.74 (2H, D, 3 Hz); 7.22 (2H, D, 3 Hz); 2.66 (2H, Q, 3 Hz); 1.34 (12H, s); 1.24 (3H, T, 3 Hz).NMR 13C, 146.68; 133.87; 127.23; 126.31; 82.58; 28.08; 23.82; 14.42.Mass spectrometry: 232-231 (M+, 6-2%); 217-216 (8-2%); 147 (19%); 146-145 (71-15%); 134 (17%); 133 (100%); 132-131 (63-21%); 118 (18%); 117 (51%); 116-115 (17-4%); 105 (18%); 104 (10%); 91 (11%); 85 (14%); 77-76 (9-2%).Ultimate Analyses:calculated %: C: 72.44%; H: 9.12%; B: 4.66%.obtained %: C: 70.22%; H: 9.25%; b: 4.39%.

Reference： [1]Journal of the American Chemical Society,2010,vol. 132,p. 11825 - 11827
[2]Patent: US2011/282090,2011,A1 .Location in patent: Page/Page column 5-6

2
[ 1585-07-5 ]
[ 61676-62-8 ]
[ 1075719-87-7 ]

Yield	Reaction Conditions	Operation in experiment
90%	With n-butyllithium; Triisopropyl borate In tetrahydrofuran; hexane at -60℃;
87%	With n-butyllithium In tetrahydrofuran; hexane at -60℃; Flow reactor;

Reference： [1]Browne, Duncan L.; Baumann, Marcus; Harji, Bashir H.; Baxendale, Ian R.; Ley, Steven V. [Organic Letters, 2011, vol. 13, # 13, p. 3312 - 3315]
[2]Newby, James A.; Huck, Lena; Blaylock, D. Wayne; Witt, Paul M.; Ley, Steven V.; Browne, Duncan L. [Chemistry - A European Journal, 2014, vol. 20, # 1, p. 263 - 271]

3
[ 1585-07-5 ]
[ 25015-63-8 ]
[ 1075719-87-7 ]

Yield	Reaction Conditions	Operation in experiment
47%	Stage #1: 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane With bis(cyclopentadienyl)titanium dichloride; lithium methanolate In neat (no solvent) for 0.5h; Inert atmosphere; Glovebox; Stage #2: 1-bromo-4-ethylbenzene In neat (no solvent) at 100℃; for 24h; Sealed tube;
	With iodine; magnesium In tetrahydrofuran at 25℃; Inert atmosphere;

Reference： [1]Wang, Xianjin; Cui, Penglei; Xia, Chungu; Wu, Lipeng [Angewandte Chemie - International Edition, 2021, vol. 60, # 22, p. 12298 - 12303][Angew. Chem., 2021, vol. 133, # 22, p. 12406 - 12411,6]
[2]Location in patent: experimental part Clary, Jacob W.; Rettenmaier, Terry J.; Snelling, Rachel; Bryks, Whitney; Banwell, Jesse; Wipke, W. Todd; Singaram, Bakthan [Journal of Organic Chemistry, 2011, vol. 76, # 23, p. 9602 - 9610]

4
[ 1585-07-5 ]
[ 73183-34-3 ]
[ 1075719-87-7 ]

Yield	Reaction Conditions	Operation in experiment
94.8%	With palladium diacetate; triphenylphosphine; cesium pivalate In 1,4-dioxane at 95℃; for 2h; Inert atmosphere;	2; 2 Example 2 Under the protection of nitrogen, 1.85g p-ethyl bromobenzene (10mmol) and 6.35g bis(pinacolato)diboron (25mmol),Dissolve in 50mL 1,4-dioxane, and then dissolve 2.57g cesium pivalate (11mmol),113mg Pd(OAc)2 (0.5mmol) and 262mg PPh3 (1mmol) in 1,4-dioxane (30ml) solution,Add to the above solution, the reaction heat is raised to 95°C, and the reaction is stirred for 2h.The reaction solution was filtered through celite, the filtrate was collected, and the filtrate was concentrated under reduced pressure.Then silica gel column chromatography (eluent: petroleum ether volume: ethyl acetate volume = 10:1),The product was 2.20 g, the yield was 94.8%, and the purity was 99.2% (HPLC).
78%	With potassium carbonate In toluene Inert atmosphere; Reflux;	16 2-(4-Etiiylphenyl)-4,4,5,5-tetramethyl-1,3,2-dloxaborolane (CP-11): Pd(PPh3)4 (1.5 g) was added to a mixture of l-bromo-4-ethylbenzene (CP- 10) (1.0.0 g, 54 mmol), pinacolatodlboron (9.5 g, 54 mmol) and potassium carbonate (15.3 g, 0.11 mol) in toluene (200 mL) under nitrogen protection. The mixture was refluxed overnight. After the mixture was cooled to room temperature, the solvent was removed under vacuum. To the residue were added water (200 mL) and ethyl acetate (200 mL). The organic phase was collected, and the aqueous phase was extracted with ethyl acetate (200 mL x 2). The organic phases were combined, dried over anhydrous sodium sulfate, and concentrated to afford CP-11 (9.8 g, 78% yield). H NMR (CDCi,, 300 MHz) δ: 7.69 (d, J = 8.4 Hz, 2H, Ph), 7.08 (d, J = 8.4 Hz, 2H, Ph), 2.54 (q, J = 6.1 Hz, 2H, CH2), 1.22 (s, 12H, plnacol-CH3), 1.13 (m, 3H, CH3).
73%	With meso-tetra(p-tolyl)porphinato-palladium(II); potassium acetate In 1,4-dioxane at 110℃; for 10h; chemoselective reaction;	General Procedure for Miyaura Borylation General procedure: Aryl/heteroaryl bromide 1 (1 mmol), B2pin2(2), B2npg2(4) orBpin (6, 1.2 mmol), and dioxane (5 mL) are taken into a 25 mLround-bottomed flask. KOAc (2 mmol) was added and stirredthe resultant mixture at room temperature for 5 min, PdII-TpTP(0.15 mol%) was added, and the contents were refluxed on preheatedoil bath at 110 °C under constant stirring in open-air.The reaction progress was ensured by TLC. After completion ofthe reaction, the mixture was cooled, dilute with water (20 mL)and extracted with tertbutylmethyl ether (3 × 10 mL). The combinedn-hexane layers were concentrated, and the crudeproduct obtained was purified by column chromatography (CC)on silica gel using a mixture of ethyl acetate and hexane (1:30)as eluent.

Reference： [1]Current Patent Assignee: NINGBO POLYTECHNIC - CN113416205, 2021, A Location in patent: Paragraph 0034-0037; 0068-0069
[2]Current Patent Assignee: PROZYMEX AS - WO2012/130299, 2012, A1 Location in patent: Page/Page column 164
[3]Rao, Kanusu Umamaheswara; Venkateswarlu, Katta [Synlett, 2018, vol. 29, # 8, p. 1055 - 1060]

5
[ 1075719-87-7 ]
[ 1401625-47-5 ]
[ 1401625-54-4 ]

Yield	Reaction Conditions	Operation in experiment
71%	With sodium carbonate In 1,4-dioxane Inert atmosphere; Reflux;	16 tert-Butyl (S)-1 -((J/^2A?)-1 -cyano-2-(4'-ethylblphenyl-4-yl)cyclopropylamlno)-1 -oxobutan-2- ylcarbamate (CP-14-(S,«,/?)): PdCI2(dppf)2 (0.1 g) was added to a mixture of CP-8-(S,R,R) (0.8 g, 1.9 mmol), CP-11 (1.9 mL, 2 ) and aqueous sodium carbonate solution (1.9 mL, 2 M) In 1,4-dioxane (30 mL) under nitrogen protection. The mixture was refluxed overnight. After the mixture was cooled to room temperature, the solvent was removed under vacuum. To the residue were added water (50 mL) and ethyl acetate (50 mL). The organic phase was collected, and the aqueous phase was extracted with ethyl acetate (50 mL x 2). The organic phases were combined, dried over anhydrous sodium sulfate, and concentrated. The crude product was purified by HPFC (PE:EA = 3:1) to afford CP-14-(S,R,R) (0.6 g, 71% yield). LC- MS: 448.1 [M+H]+.

Reference： [1]Current Patent Assignee: PROZYMEX AS - WO2012/130299, 2012, A1 Location in patent: Page/Page column 165

6
[ 1075719-87-7 ]
[ 1401625-47-5 ]
[ 1401624-48-3 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: sodium carbonate / 1,4-dioxane / Inert atmosphere; Reflux 2: formic acid / 4 h / 20 °C

Reference： [1]Current Patent Assignee: PROZYMEX AS - WO2012/130299, 2012, A1

Yield	Reaction Conditions	Operation in experiment
99%	Stage #1: With iodine; magnesium In tetrahydrofuran at 25℃; for 3.083h; Inert atmosphere; Stage #2: With hydrogenchloride In tetrahydrofuran; water at 0 - 25℃; for 0.666667h;	EXAMPLE 3 Preparation of Aryl and Alkyl-Pinacolboranate Esters Under Barbier-Type Conditions General procedure: EXAMPLE 3Preparation of Aryl and Alkyl-Pinacolboranate Esters Under Barbier-Type Conditions[0075] The following procedure for the preparation m-tolyl pinacolborane isrepresentative. A 25-mL round-bottom flask equipped with a magnetic stir bar was charged with magnesium turnings (0.058 g, 2.4 mmol) and was activated by addition of iodine crystals and warming until iodine sublimed. The flask was cooled to 25 °C and was purged with Ar. THF (3.5 mL) was added to the flask, followed by the addition of neatpinacolborane (0.29 mL, 2.0 mmol). m-Tolyl bromide (0.243 mL, 2.0 mmol) was then added drop wise over five minutes with constant stirring at 25 °C. The reaction was complete after 3 h as evidenced by the disappearance of pinacolborane starting material ( +27.7, d, J=173.9 Hz), and the appearance of a singlet at +30.6 ppm via nB-NMR. The reaction was then cooled to 0°C (ice bath) and acidified with 3 M aqueous HC1 (3 mL) (CAUTION: hydrogen evolution). After 10 min of stirring the reaction mixture was warmed to 25 °C and stirred for an additional 30 min. Table entries 4, 6, 7, 8 were quenched with aqueous NH C1 (2.5 mL, 0.16 M). The reaction mixture was then transferred to a separatory funnel and extracted with diethyl ether (3 x 15 mL). The combined organic layers were dried over anhydrous MgS04, filtered, and dried under vacuo (25°C, 1 Torr) to afford m-tolyl pinacolborane as a pale yellow oil. The results for the other pinacolborane esters prepared by this method are summarized in Table 2.

8
[ 58530-53-3 ]
[ 1075719-87-7 ]
[ 1514914-34-1 ]

Yield	Reaction Conditions	Operation in experiment
84%	With palladium diacetate; triphenylphosphine; potassium hydroxide; In acetonitrile; at 70℃; for 24h;Inert atmosphere;	General procedure: <strong>[58530-53-3]2,4-dibromopyridine</strong> (0.12 g, 0.50 mmol), phenylboronic acid pinacol ester (0.11 g, 0.55 mmol), KOH (56 mg, 1.0 mmol), Pd(OAc)2 (11 mg, 5 mol %), PPh3 (52 mg, 20 mol %) were dissolved in CH3CN (6 mL). The reaction was stirred at 70 C under nitrogen atmosphere for 24 h and then cooled. The solid was filtrated off and the filtrate was concentrated. The crude product was then dissolved in CH2Cl2 (10 mL) and the solution was washed with water (10 mL*3) and brine (10 mL), and dried over sodium sulfate. Upon evaporation, the resulting residue was subjected to column chromatography (petroleum ether/AcOEt, 400:1) to give 3w (104 mg, 89%) as a colorless liquid.

Reference： [1]Tetrahedron,2013,vol. 69,p. 10996 - 11003

9
[ 100-41-4 ]
[ 25015-63-8 ]
[ 1075719-87-7 ]
[ 1075719-83-3 ]

Yield	Reaction Conditions	Operation in experiment
	With bis(1,2-bis(dimethylphosphino)ethane)dimethyliron In neat (no solvent) at 20℃; for 72h; Glovebox; Schlenk technique; Inert atmosphere; Irradiation; Overall yield = 73 %; Overall yield = 85 mg; regioselective reaction;
	With C₄₇H₅₅N₂Ni at 100℃; for 24h; Inert atmosphere; Glovebox; Sealed tube; Overall yield = 82 percent;

Reference： [1]Dombray, Thomas; Werncke, C. Gunnar; Jiang, Shi; Grellier, Mary; Vendier, Laure; Bontemps, Sébastien; Sortais, Jean-Baptiste; Sabo-Etienne, Sylviane; Darcel, Christophe [Journal of the American Chemical Society, 2015, vol. 137, # 12, p. 4062 - 4065]
[2]Das, Arpan; Hota, Pradip Kumar; Mandal, Swadhin K. [Organometallics, 2019, vol. 38, # 17, p. 3286 - 3293]

10
[ 100-41-4 ]
[ 25015-63-8 ]
[ 1075719-87-7 ]
[ 1075719-83-3 ]
2-(2-ethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane [ No CAS ]
[ 174090-36-9 ]

Yield	Reaction Conditions	Operation in experiment
1: 1 %Chromat. 2: 22 %Chromat. 3: 12 %Chromat. 4: 15 %Chromat.	With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; 1,3-dicyclohexyl-1H-imidazol-3-ium chloride; sodium t-butanolate at 100℃; for 20h; Inert atmosphere; Overall yield = 50 %; Overall yield = 145 mg;

Reference： [1]Furukawa, Takayuki; Tobisu, Mamoru; Chatani, Naoto [Chemical Communications, 2015, vol. 51, # 30, p. 6508 - 6511]

11
[ 1075719-87-7 ]
[ 134856-58-9 ]
4-ethyl-1-(4-(trimethylsilylethynyl)phenyl)benzene [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
66%	With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In tetrahydrofuran; water at 65℃; for 5h; Inert atmosphere;

Reference： [1]Buendia, Julien; Darses, Benjamin; Dauban, Philippe [Angewandte Chemie - International Edition, 2015, vol. 54, # 19, p. 5697 - 5701][Angew. Chem., 2015, vol. 127, # 19, p. 5789 - 5793,5][Angewandte Chemie, 2015, vol. 127, # 19, p. 5789 - 5793,5]

12
[ 1075719-87-7 ]
C₃₃H₃₆N₂O₃S₂Si [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / tetrahydrofuran; water / 5 h / 65 °C / Inert atmosphere 2.1: Rh<SUB>2</SUB>(S-N-(1,8-naphthoyl)alanine)<SUB>4</SUB> / methanol; 1,1,2,2-tetrachloroethane / 0.08 h / Molecular sieve; Inert atmosphere; Sealed tube 2.2: 72 h / -78 - -35 °C / Molecular sieve; Inert atmosphere; Sealed tube

13
[ 1075719-87-7 ]
C₃₆H₃₂N₂O₃S₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / tetrahydrofuran; water / 5 h / 65 °C / Inert atmosphere 2.1: Rh<SUB>2</SUB>(S-N-(1,8-naphthoyl)alanine)<SUB>4</SUB> / methanol; 1,1,2,2-tetrachloroethane / 0.08 h / Molecular sieve; Inert atmosphere; Sealed tube 2.2: 72 h / -78 - -35 °C / Molecular sieve; Inert atmosphere; Sealed tube 2.3: 70 °C / Molecular sieve; Inert atmosphere; Sealed tube

14
[ 1075719-87-7 ]
C₄₀H₃₄N₂O₃S₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / tetrahydrofuran; water / 5 h / 65 °C / Inert atmosphere 2.1: Rh<SUB>2</SUB>(S-N-(1,8-naphthoyl)alanine)<SUB>4</SUB> / methanol; 1,1,2,2-tetrachloroethane / 0.08 h / Molecular sieve; Inert atmosphere; Sealed tube 2.2: 72 h / -78 - -35 °C / Molecular sieve; Inert atmosphere; Sealed tube 2.3: 70 °C / Molecular sieve; Inert atmosphere; Sealed tube

15
[ 100-41-4 ]
[ 73183-34-3 ]
[ 1075719-87-7 ]
[ 1075719-83-3 ]
C₂₀H₃₂B₂O₄ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
11%	With (6,6’-dimethoxy-[1,1 ‘-biphenyl]-2,2’-diyl)bis(bis(3 ,5-dimethyl-phenyl)phosphine); [(1,5-cyclooctadiene)(OH)iridium(I)]2 In hexane at 85℃; for 20h; Inert atmosphere; Glovebox; Sealed tube; Overall yield = 80 %; regioselective reaction;

Reference： [1]Saito, Yutaro; Segawa, Yasutomo; Itami, Kenichiro [Journal of the American Chemical Society, 2015, vol. 137, # 15, p. 5193 - 5198]

16
[ 1585-07-5 ]
2-(4-iodobutoxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane [ No CAS ]
[ 1075719-87-7 ]

Yield	Reaction Conditions	Operation in experiment
88%	With magnesium In tetrahydrofuran at 25℃; for 3h; Inert atmosphere;	General procedure for the synthesis of compounds 1a-1m General procedure: To a solution containing 4-IboxBpin (0.651 g,2.0 mmol) and anhydrous THF (8 mL) under Ar, Mg turnings (0.048 g,2.0 mmol) were added. The corresponding halide reagent (2.0 mmol) wasthen introduced dropwise over 5 min with constant stirring at 25 C. Thereaction was complete after 3 h, as evidenced by the disappearance of4-IboxBpin (d +21.6) via 11B NMR. 1 M HCl (3 mL) was then added to thereaction flask and left to stir for 5 min. The reaction mixture was thentransferred to a separatory funnel and extracted with diethyl ether(3 15 mL). The combined organic layers were dried over anhydrous MgSO4,filtered, and dried in vacuo, (25 C, 1 Torr) to afford the correspondingpinacolboronate.

Reference： [1]Murphy, Chris L.; Hall, Aaron; Roberts, Emily J.; Ryan, Matthew D.; Clary, Jacob W.; Singaram, Bakthan [Tetrahedron Letters, 2015, vol. 56, # 23, p. 3032 - 3033]

17
[ 25015-63-8 ]
[ 1075719-87-7 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 3 steps 1: pentane / 0.5 h / 25 °C / Inert atmosphere 2: pentane / 3 h / 25 °C / Inert atmosphere 3: magnesium / tetrahydrofuran / 3 h / 25 °C / Inert atmosphere

Reference： [1]Murphy, Chris L.; Hall, Aaron; Roberts, Emily J.; Ryan, Matthew D.; Clary, Jacob W.; Singaram, Bakthan [Tetrahedron Letters, 2015, vol. 56, # 23, p. 3032 - 3033]

18
C₆H₁₂BIO₂ [ No CAS ]
[ 1075719-87-7 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: pentane / 3 h / 25 °C / Inert atmosphere 2: magnesium / tetrahydrofuran / 3 h / 25 °C / Inert atmosphere

Reference： [1]Murphy, Chris L.; Hall, Aaron; Roberts, Emily J.; Ryan, Matthew D.; Clary, Jacob W.; Singaram, Bakthan [Tetrahedron Letters, 2015, vol. 56, # 23, p. 3032 - 3033]

19
[ 1075719-87-7 ]
[ 123-07-9 ]

Yield	Reaction Conditions	Operation in experiment
94%	With [Cu₆I₂(μ⁴-I)₂(μ⁴-5-phpymt)₂]; triethylamine In water; acetonitrile for 48h; UV-irradiation;

Reference： [1]Zhang, Meng-Juan; Li, Hong-Xi; Li, Hai-Yan; Lang, Jian-Ping [Dalton Transactions, 2016, vol. 45, # 44, p. 17759 - 17769]

20
[ 1075719-87-7 ]
methyl 4-(bromo(trifluoromethoxy)methyl)benzoate [ No CAS ]
(R)-methyl 4-((4-ethylphenyl)(trifluoromethoxy)methyl)benzoate [ No CAS ]
methyl 4-((4-ethylphenyl)(trifluoromethoxy)methyl)benzoate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
84 % ee	Stage #1: 2-(4-ethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane With nickel(II) bromide dimethoxyethane; n-butyllithium; (3aR,8aS)-2-(3-methylpyridin-2-yl)-8,8a-dihydro-3aH-indeno[1,2-d]oxazole In tetrahydrofuran; hexane at 0℃; for 0.333333h; Inert atmosphere; Glovebox; Schlenk technique; Stage #2: methyl 4-(bromo(trifluoromethoxy)methyl)benzoate In tetrahydrofuran; hexane at 0℃; for 5h; Inert atmosphere; Glovebox; Schlenk technique; Overall yield = 82 %; Overall yield = 139 mg; enantioselective reaction;

21
[ 29786-93-4 ]
[ 1075719-87-7 ]
C₁₈H₃₀BO₂^(1-)*Li⁽¹⁺⁾ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With nickel(II) bromide dimethoxyethane; (3aR,8aS)-2-(3-methylpyridin-2-yl)-8,8a-dihydro-3aH-indeno[1,2-d]oxazole In tetrahydrofuran; hexane at 0℃; for 0.333333h; Inert atmosphere; Glovebox; Schlenk technique;
	In tetrahydrofuran; hexane at 20℃; for 1h;

Reference： [1]Huang, Weichen; Wan, Xiaolong; Shen, Qilong [Angewandte Chemie - International Edition, 2017, vol. 56, # 39, p. 11986 - 11989][Angew. Chem., 2017, vol. 129, # 39, p. 12148 - 12151,4]
[2]Li, Jing; Wang, Xiaoyu; Wang, Zhanwei; Shi, Yian [Organic Letters, 2021, vol. 23, # 22, p. 8958 - 8962]

22
[ 73183-34-3 ]
[ 117357-15-0 ]
[ 1075719-87-7 ]

Yield	Reaction Conditions	Operation in experiment
87%	With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; potassium phosphate; tricyclohexylphosphine In tetrahydrofuran at 20℃; Glovebox; Inert atmosphere;

Reference： [1]Dong, Jie; Guo, Hui; Hu, Qiao-Sheng [European Journal of Organic Chemistry, 2017, vol. 2017, # 47, p. 7087 - 7090]

23
[ 1075719-87-7 ]
[ 174680-55-8 ]
3-benzyl-5-(4-ethylphenyl)pyrazine-2-amine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
91%	With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate In ethanol; water; toluene at 100℃; for 12h; Inert atmosphere;	14.14-1 Synthesis Example 14-1 Under a nitrogen atmosphere, 3-benzyl-5-bromopyrazine-2-amine (100.0 mg, 0.3 mmol, 1 eq.) and 2-(4-ethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (140.4 mg, 0.6 mmol, 1.6 eq.) were dissolved in ethanol (1 ml) and toluene (6 ml). To the solution was added 1 M aqueous sodium carbonate solution (1.6 ml) and the mixture was stirred at room temperature. The reaction solution was degassed under vacuum. To the solution was added a catalytic amount of tetrakis(triphenylphosphine)palladium (0) (about 1 cup of micro spatula) and the mixture was degassed again under vacuum and then stirred at 100° C. overnight (12 hours). After allowing the mixture to cool to room temperature, the mixture was filtered through Celite to remove palladium catalyst. The resulting residue was extracted with ethyl acetate, washed with distilled water and saturated brine, dried over sodium sulfate, and then concentrated under reduced pressure. The resulting residue was purified by flash column chromatography (eluent: hexane/ethyl acetate=7/3) to obtain 3-benzyl-5-(4-ethylphenyl)pyrazine-2-amine as a yellow solid (100.4 mg, 0.3 mmol, 91%). 1H-NMR (500 MHz, CDCl3): δ (ppm)=8.37 (s, 1H), 7.86 (d, J=8.0 Hz, 2H), 7.33-7.25 (m, 7H), 4.37 (s, 2H), 4.18 (s, 2H), 2.70 (t, J=7.4 Hz, 2H), 1.28-1.25 (m, 3H). 13C-NMR (150 MHz, CDCl3): δ (ppm)=15.78, 28.79, 41.42, 76.90, 77.16, 77.41, 125.91, 127.16, 128.48, 128.71, 129.11, 134.87, 136.95, 137.44, 140.67, 142.96, 144.47, 151.66.

Reference： [1]Current Patent Assignee: KEIO UNIVERSITY; NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY; THE UNIVERSITY OF TOKYO - US2018/273539, 2018, A1 Location in patent: Paragraph 0106-0108

24
[ 1075719-87-7 ]
C₂₈H₂₅N₃O₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / ethanol; toluene; water / 12 h / 100 °C / Inert atmosphere 2: hydrogenchloride / ethanol; water / 21 h / 0 - 80 °C / Inert atmosphere

Reference： [1]Current Patent Assignee: KEIO UNIVERSITY; NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY; THE UNIVERSITY OF TOKYO - US2018/273539, 2018, A1

25
[ 1075719-87-7 ]
C₂₈H₂₅N₃O [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / ethanol; toluene; water / 12 h / 100 °C / Inert atmosphere 2: hydrogenchloride / ethanol; water / 14 h / 0 - 80 °C / Inert atmosphere

Reference： [1]Current Patent Assignee: KEIO UNIVERSITY; NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY; THE UNIVERSITY OF TOKYO - US2018/273539, 2018, A1

26
[ 100-41-4 ]
[ 73183-34-3 ]
[ 1075719-87-7 ]
[ 1075719-83-3 ]

Yield	Reaction Conditions	Operation in experiment
	With C₃₅H₅₉FeNP₂ at 100℃; for 18h; Schlenk technique; Glovebox; Inert atmosphere; Overall yield = 28 %;

Reference： [1]Kato, Takeru; Kuriyama, Shogo; Nakajima, Kazunari; Nishibayashi, Yoshiaki [Chemistry - An Asian Journal, 2019, vol. 14, # 12, p. 2097 - 2101]

27
C₂₀H₁₇S₂⁽¹⁺⁾*CF₃O₃S^(1-) [ No CAS ]
[ 73183-34-3 ]
[ 1075719-87-7 ]

Yield	Reaction Conditions	Operation in experiment
86%	With dmap; (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile In acetonitrile at 20℃; for 8h; Irradiation; Inert atmosphere;
36 mg	With palladium diacetate; sodium pivalate; XPhos In dichloromethane; acetone at 20℃; for 12h; Inert atmosphere;

Reference： [1]Wu, Jie; Wang, Zengwei; Chen, Xiao-Yue; Wu, Yichen; Wang, Daoming; Peng, Qian; Wang, Peng [Science China Chemistry, 2020, vol. 63, # 3, p. 336 - 340]
[2]Chen, Xiao-Yue; Huang, Yu-Hao; Zhou, Jian; Wang, Peng [Chinese Journal of Chemistry, 2020, vol. 38, # 11, p. 1269 - 1272]

28
[ 100-41-4 ]
[ 1075719-87-7 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: dichloromethane / 1 h / -40 - 20 °C 2: dmap; (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile / acetonitrile / 8 h / 20 °C / Irradiation; Inert atmosphere
	Multi-step reaction with 2 steps 1: dichloromethane / 1.5 h / -40 - 20 °C / Schlenk technique; Inert atmosphere 2: palladium diacetate; XPhos; sodium pivalate / acetone; dichloromethane / 12 h / 20 °C / Inert atmosphere

29
[ 100-41-4 ]
[ 73183-34-3 ]
[ 1075719-87-7 ]
[ 1075719-83-3 ]
2-(2-ethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane [ No CAS ]
[ 165904-22-3 ]

Yield	Reaction Conditions	Operation in experiment
	With basolite C₃₀₀ In neat (no solvent) at 100℃; for 24h;	2.4. Experimental procedure General procedure: In a 25 mL round bottom flask, toluene (1 mL), Cu3(BTC)2 (30 mg),1 (127 mg, 0.5 mmol) were charged and this slurry was stirred at 100°C. The borylation of toluene was monitored by gas chromatography(GC) and the conversion of 1 was determined at different time intervals.Similar experimental procedures were performed with radicalquenchers like TEMPO and 2,6-di-t-butyl-4-methylphenol with appropriateamount mentioned in the table. The product identity was confirmedby analyzing the reaction mixture by GC-MS. Conversion of theborylation reaction and selectivity of the products were determined byAgilent GC.

Reference： [1]Dhakshinamoorthy, Amarajothi; García, Cristina Vallés; Concepcion, Patricia; Garcia, Hermenegildo [Catalysis Today, 2021, vol. 366, p. 212 - 217]

30
[ 459-47-2 ]
[ 73183-34-3 ]
[ 1075719-87-7 ]
[ 100-41-4 ]

Yield	Reaction Conditions	Operation in experiment
68%; 22%Chromat.	With tetramethylammonium fluoride; 2-mercaptopyridine sodium salt; In acetonitrile; at 30 - 35℃; for 24h;Irradiation; Inert atmosphere;	General procedure: To a 9 mL snap vial with magnetic stirring bar, B2pin2 (0.6 mmol), TMAF (0.6 mmol), sodiumpyridine-2-thiolate (30 mol%) were added. The vial was evacuated and back filled with N2 for threetimes. A solution of fluoroarene (0.2 mmol) in dry MeCN (2 mL) was added by syringe. The mixturewas irradiated with a 385-390 nm LED (with aluminum block cooling to keep the internaltemperature of the reaction mixture at 30-35 oC) under N2 atmosphere. After 24 h, the reactionmixture was diluted with EA (5 mL) and filtered through a pad of Celite. After filtration, the filtratewas concentrated under reduced pressure. The residue was purified by silica gel columnchromatography (eluent: hexane/EtOAc) to give the corresponding boronate esters.

Reference： [1]Chem,2021,vol. 7,p. 1653 - 1665

31
[ 1075719-87-7 ]
C₁₇H₂₈N₂O [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: tetrahydrofuran; hexane / 1 h / 20 °C 2: copper(I) bromide / tetrahydrofuran; hexane / 1 h / 20 °C

Reference： [1]Li, Jing; Wang, Xiaoyu; Wang, Zhanwei; Shi, Yian [Organic Letters, 2021, vol. 23, # 22, p. 8958 - 8962]

32
[ 1075719-87-7 ]
[ 171364-81-1 ]

Yield	Reaction Conditions	Operation in experiment
81%	With hydrogenchloride In water; acetonitrile at 20℃; for 8h; Irradiation;

Reference： [1]Niu, Kaikai; Shi, Xiaodi; Ding, Ling; Liu, Yuxiu; Song, Hongjian; Wang, Qingmin [ChemSusChem, 2022, vol. 15, # 2]

33
[ 100-41-4 ]
[ 25015-63-8 ]
[ 1075719-87-7 ]
[ 1075719-83-3 ]
C₂₀H₃₂B₂O₄ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With bis(η⁴-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 2’,7’-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4,5-diaza-9,9’-spirobifluorene In 1,4-dioxane at 90℃; for 16h; regioselective reaction;

Reference： [1]Ramadoss, Boobalan; Jin, Yushu; Asako, Sobi; Ilies, Laurean [Science, 2022, vol. 375, # 6581, p. 658 - 663]

Same Skeleton Products

Related Products

Historical Records

Related Functional Groups of
[ 1075719-87-7 ]

Organoboron

[ 911708-01-5 ]

2-(4-Benzylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.98

[ 1075719-83-3 ]

2-(3-Ethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.98

[ 325142-91-4 ]

2-(4-Isopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.98

[ 1033753-01-3 ]

2-(4-Isobutylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.98

[ 651030-55-6 ]

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneethanol

Similarity: 0.98

Aryls

[ 911708-01-5 ]

2-(4-Benzylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.98

[ 1075719-83-3 ]

2-(3-Ethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.98

[ 325142-91-4 ]

2-(4-Isopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.98

[ 1033753-01-3 ]

2-(4-Isobutylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.98

[ 651030-55-6 ]

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneethanol

Similarity: 0.98

Esters

[ 911708-01-5 ]

2-(4-Benzylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.98

[ 1075719-83-3 ]

2-(3-Ethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.98

[ 325142-91-4 ]

2-(4-Isopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.98

[ 1033753-01-3 ]

2-(4-Isobutylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.98

[ 651030-55-6 ]

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneethanol

Similarity: 0.98

Ghs Precautionary Statements

Precautionary Statements-General
Code	Phrase
P101	If medical advice is needed,have product container or label at hand.
P102	Keep out of reach of children.
P103	Read label before use
Prevention
Code	Phrase
P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P210	Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211	Do not spray on an open flame or other ignition source.
P220	Keep/Store away from clothing/combustible materials.
P221	Take any precaution to avoid mixing with combustibles
P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P230	Keep wetted
P231	Handle under inert gas.
P232	Protect from moisture.
P233	Keep container tightly closed.
P234	Keep only in original container.
P235	Keep cool
P240	Ground/bond container and receiving equipment.
P241	Use explosion-proof electrical/ventilating/lighting/equipment.
P242	Use only non-sparking tools.
P243	Take precautionary measures against static discharge.
P244	Keep reduction valves free from grease and oil.
P250	Do not subject to grinding/shock/friction.
P251	Pressurized container: Do not pierce or burn, even after use.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
P282	Wear cold insulating gloves/face shield/eye protection.
P283	Wear fire/flame resistant/retardant clothing.
P284	Wear respiratory protection.
P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
P235 + P410	Keep cool. Protect from sunlight.
Response
Code	Phrase
P301	IF SWALLOWED:
P304	IF INHALED:
P305	IF IN EYES:
P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
P309	IF exposed or if you feel unwell:
P310	Immediately call a POISON CENTER or doctor/physician.
P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P313	Get medical advice/attention.
P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
P322
P330	Rinse mouth.
P331	Do NOT induce vomiting.
P332	IF SKIN irritation occurs:
P333	If skin irritation or rash occurs:
P334	Immerse in cool water/wrap n wet bandages.
P335	Brush off loose particles from skin.
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
P338	Remove contact lenses, if present and easy to do. Continue rinsing.
P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
{[ item.p_purity ]}	{[ item.pr_size ]}	{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]}	{[ getRatePrice(item.pr_usd, 1,1) ]}	Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]}	{[ item.pr_usastock ]}	Inquiry -	{[ item.pr_chinastock ]}	Inquiry -

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 1075719-87-7 ] {[proInfo.proName]}

Quality Control of [ 1075719-87-7 ]

Related Doc. of [ 1075719-87-7 ]

Product Details of [ 1075719-87-7 ]

Safety of [ 1075719-87-7 ]

Application In Synthesis of [ 1075719-87-7 ]

[ 1075719-87-7 ] Synthesis Path-Downstream 1~33

Related Functional Groups of [ 1075719-87-7 ]

Organoboron

Aryls

Esters

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 1075719-87-7 ]