Home Cart 0 Sign in  

[ CAS No. 1079402-25-7 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 1079402-25-7
Chemical Structure| 1079402-25-7
Structure of 1079402-25-7 *Storage: {[proInfo.prStorage]}

Quality Control of [ 1079402-25-7 ]

Related Doc. of [ 1079402-25-7 ]

SDS
Alternatived Products of [ 1079402-25-7 ]
Alternatived Products of [ 1079402-25-7 ]

Product Details of [ 1079402-25-7 ]

CAS No. :1079402-25-7MDL No. :MFCD12025981
Formula : C8H8BF3O4 Boiling Point : -
Linear Structure Formula :-InChI Key :N/A
M.W :235.95Pubchem ID :-
Synonyms :

Computed Properties of [ 1079402-25-7 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 1079402-25-7 ]

Signal Word:WarningClass:
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362-P403+P233-P501UN#:
Hazard Statements:H302-H312-H332Packing Group:
GHS Pictogram:

Application In Synthesis of [ 1079402-25-7 ]

  • Downstream synthetic route of [ 1079402-25-7 ]

[ 1079402-25-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1049730-91-7 ]
  • [ 1079402-25-7 ]
YieldReaction ConditionsOperation in experiment
43% To a stirred solution of 2-Bromo-4-methoxy-1-trifluoromethoxy-benzene (Preparation 59, 19.0 g, 73.9 mmol) in anhydrous tetrahydrofuran (400 ml) was added n-butyl lithium (2.5M solution in hexanes, 44.2 ml, 110.9 mmol) while maintaining the temperature below -7O0C under an atmosphere of nitrogen. The resulting solution was stirred at -7O0C for 1 hour. Tri-/sopropyl borate (20.9 g, 110.9 mmol) was added and the mixture stirred at -7O0C for an additional 2 hours. The reaction mixture was <n="176"/>quenched with saturated ammonium chloride aqueous solution (400 ml). The resulting mixture was acidified to pH~5 by addition of hydrochloric acid (1 N aqueous solution). The layers were separated and the organic layer was washed with water (200 ml) then dried over anhydrous MgSO4 (s), filtered and evaporated in vacuo. Residue was purified by recrystallization from ethyl acetate: petroleum ether (2 ml:50 ml) to afford the title compound as a white solid (7.5 g, 43%).1HNMR (c^DMSO): 3.76 (s, 3H), 6.99 (dd, 1 H), 7.06 (d, 1 H), 7.18 (dd, 1 H), 8.36 (s, 2H).
Historical Records