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Chemical Structure| 107971-34-6 Chemical Structure| 107971-34-6

Structure of 107971-34-6

Chemical Structure| 107971-34-6

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Product Details of [ 107971-34-6 ]

CAS No. :107971-34-6
Formula : C12H14O5S
M.W : 270.30
SMILES Code : O=S(C1=CC=C(C)C=C1)(OCC(CC2)OC2=O)=O
MDL No. :MFCD00830236

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Application In Synthesis of [ 107971-34-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 107971-34-6 ]

[ 107971-34-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 10374-51-3 ]
  • [ 98-59-9 ]
  • [ 107971-34-6 ]
YieldReaction ConditionsOperation in experiment
76% With pyridine; In dichloromethane; EXAMPLE 57 (+-)-Dihydro-5-(p-Toluenesulfonyloxymethyl)-2(3H) -Furanone STR90 p-Toluenesulfonyl chloride (23.65 g, 124.03 mmol) was added portion wise to a solution of (+-)-dihydro-5-hydroxymethyl-2(3H)-furanone (example 56) (11.07 g, 95.43 mmol) and pyridine (15.4 mL, 190.86 mmol) in methylene chloride (300 mL) at 0 C. The solution was allowed to warm to rt and stirred overnight. The solution was then washed with water (2*100 mL), 0.5 n HCl until the washings were acidic and finally with saturated NaHCO3. After drying and concentrating, the residue was triturated with toluene to give the title compound as a white solid (19.63 g, 76%). 1 H NMR (300 MHz, CDCl3) delta: 7.79 (d, 2H, Ar-H, J=8.3 Hz), 7.38 (d, 2H, Ar-H, J=8.3 Hz), 4.69 (m, 1H, H-5), 4.20 (dd, 1H, H-6, J=3.4 HZ and 11.0 Hz), 4.14 (dd, 1H, H-6', J=4.1 HZ and 11.0 Hz), 2.5 (m, 2H, H-3), 2.44 (s, 3H, Ar-CH3), 2.3, 2.1 (m, 2H, H-4).
 

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