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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 112-18-5 Chemical Structure| 112-18-5

Structure of 112-18-5

Chemical Structure| 112-18-5

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Product Details of [ 112-18-5 ]

CAS No. :112-18-5
Formula : C14H31N
M.W : 213.40
SMILES Code : CCCCCCCCCCCCN(C)C
MDL No. :MFCD00008970
InChI Key :YWFWDNVOPHGWMX-UHFFFAOYSA-N
Pubchem ID :8168

Safety of [ 112-18-5 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314-H410
Precautionary Statements:P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P391
Class:8
UN#:2735
Packing Group:

Application In Synthesis of [ 112-18-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 112-18-5 ]
  • Downstream synthetic route of [ 112-18-5 ]

[ 112-18-5 ] Synthesis Path-Upstream   1~3

  • 1
  • [ 143-15-7 ]
  • [ 124-40-3 ]
  • [ 112-18-5 ]
  • [ 3282-73-3 ]
YieldReaction ConditionsOperation in experiment
40% at 20 - 25℃; for 20 h; A mixture of a 38percent aqueous solution of dimethylamine (12.5 mL, 93.8 mmol) and dodecyl bromide (11.7 g, 46.9 mmol) in benzene (15 mL) was stirred at 20—25 °C for 20 h. Then, a 50percent aqueous solution of NaOH (1.9 g, 46.9 mmol) was added to the reaction mixture, and the resulting mixture was evaporated in vacuo. The residue was dissolved in CHCl3 (20 mL), the formed precipitate was filtered off, and the filtrate was evaporated in vacuo. According to the 1H NMR spectral data, the isolated mixture contained amine 6a (4.1 g, 40percent), N,N-didodecyl-N,N-dimethylammonium bromide (4.9 g, 46percent), and unreacted dodecyl bromide (1.7 g, 14percent).
References: [1] Russian Chemical Bulletin, 2014, vol. 63, # 11, p. 2445 - 2454[2] Izv. Akad. Nauk, Ser. Khim., 2014, # 11, p. 2445 - 2454.
  • 2
  • [ 112-18-5 ]
  • [ 143-15-7 ]
  • [ 3282-73-3 ]
References: [1] Chemical Communications, 2006, # 44, p. 4575 - 4577.
[2] Journal of Organic Chemistry, 1984, vol. 49, # 20, p. 3774 - 3778.
[3] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1987, p. 541 - 546.
[4] Journal of Physical Chemistry, 1983, vol. 87, # 4, p. 538 - 540.
[5] Bulletin of the Chemical Society of Japan, 2003, vol. 76, # 10, p. 1903 - 1910.
[6] Patent: WO2005/97729, 2005, A2, . Location in patent: Page/Page column 49-50; 56-57.
  • 3
  • [ 111-24-0 ]
  • [ 112-18-5 ]
  • [ 18464-25-0 ]
References: [1] Molecules, 2011, vol. 16, # 1, p. 319 - 335.
[2] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 24, p. 5824 - 5828.
[3] Pharmaceutical Chemistry Journal, 1968, # 5, p. 247 - 250[4] Khimiko-Farmatsevticheskii Zhurnal, 1968, # 5, p. 15 - 18.
 

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