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Chemical Structure| 112106-91-9 Chemical Structure| 112106-91-9

Structure of 112106-91-9

Chemical Structure| 112106-91-9

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Product Details of [ 112106-91-9 ]

CAS No. :112106-91-9
Formula : C10H11NO2
M.W : 177.20
SMILES Code : O=C(C1=CC=CC2=C1NCC2)OC
MDL No. :MFCD09954772
InChI Key :IMJZMELPOAMWJA-UHFFFAOYSA-N
Pubchem ID :14072919

Safety of [ 112106-91-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P260-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338

Application In Synthesis of [ 112106-91-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 112106-91-9 ]

[ 112106-91-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 93247-78-0 ]
  • [ 112106-91-9 ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride; In 1,4-dioxane; water; EXAMPLE 6 (Preparation of starting material) STR15 1.75 g of <strong>[93247-78-0]indole-7-carboxylic acid methyl ester</strong> and 2.92 g of borane-trimethylamine complex are dissolved in 10 ml of dioxane. To the resulting solution, 2 ml of concentrated hydrochloric acid are added. The reaction solution is heated under reflux for 30 minutes, and then cooled to room temperature. 10 ml of 6N hydrochloric acid are added to the reaction solution, which is then refluxed under heating for 15 minutes, and thereafter cooled to room temperature. The reaction solution is poured into 50 ml of water. The resulting mixture is neutralized with a 2N aqueous sodium hydroxide solution, and then extractd with ether. The organic layer is washed with a saturated aqueous sodium chloride solution, and dried over anhydrous sodium sulfate. After the solvent has been distilled off, 1.26 g of 2,3-dihydro<strong>[93247-78-0]indole-7-carboxylic acid methyl ester</strong> are obtained, mp. 70° to 73° C.
 

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