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Chemical Structure| 1126779-29-0 Chemical Structure| 1126779-29-0

Structure of 1126779-29-0

Chemical Structure| 1126779-29-0

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Product Details of [ 1126779-29-0 ]

CAS No. :1126779-29-0
Formula : C7H5BrN2O
M.W : 213.03
SMILES Code : N#CC1=CC(Br)=CN(C)C1=O
MDL No. :MFCD18072694

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Application In Synthesis of [ 1126779-29-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1126779-29-0 ]

[ 1126779-29-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 405224-22-8 ]
  • [ 74-88-4 ]
  • [ 1126779-29-0 ]
YieldReaction ConditionsOperation in experiment
With caesium carbonate; In N,N-dimethyl-formamide; for 2.0h; Reference Example 10; 5-bromo-1-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile To a solution of <strong>[405224-22-8]5-bromo-2-oxo-1,2-dihydropyridine-3-carbonitrile</strong> (507 mg) in DMF (5 mL) were added cesium carbonate (1.66 g) and methyl iodide (0.19 mL), and the mixture was stirred at 0° C. for 2 hr. The reaction mixture was poured into water, and the mixture was extracted with ethyl acetate. The ethyl acetate layer was washed with water, dried over anhydrous magnesium sulfate and concentrated. The residue was purified by column chromatography (hexane-ethyl acetate) to give the title compound (317 mg) as a solid.1H-NMR (CDCl3) delta: 3.61 (3H, s), 7.69 (1H, d), 7.85 (1H, d).
 

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