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Chemical Structure| 1132690-71-1 Chemical Structure| 1132690-71-1

Structure of 1132690-71-1

Chemical Structure| 1132690-71-1

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Product Details of [ 1132690-71-1 ]

CAS No. :1132690-71-1
Formula : C10H11N3O2
M.W : 205.22
SMILES Code : O=C1C2=C(NC(N)=N1)C(CCCC3)=C3O2
MDL No. :MFCD24613747

Safety of [ 1132690-71-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 1132690-71-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1132690-71-1 ]

[ 1132690-71-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1132690-71-1 ]
  • [ 392338-15-7 ]
  • [ 1148116-17-9 ]
YieldReaction ConditionsOperation in experiment
59% With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine; In 1,4-dioxane; at 20℃; for 72h; To a suspension of the compound obtained in reference example 7 (1 g, 4.88 mmol) in 1 ,4-dioxane (50 mL), triethylamine (12.5 mL), PyBOP (2.54 g, 4.88 mmol) and reference example 1 (1.47 g, 7.34 mmol) were added. The resulting suspension was stirred at room temperature for 72 hours and was then concentrated to dryness. The crude product obtained was partitioned between dichloromethane and 0.5 N NaOH. The organic phase was dried over Na2SO4 and concentrated to dryness. The crude product obtained was purified by chromatography on silica gel using EtOAc/MeOH mixtures of increasing polarity as eluent, to afford 1.12 g of the desired compound (yield: 59%).LC-MS (Method 2): tR = 2.38 min; m/z 388 (MH+)
 

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