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Chemical Structure| 113791-14-3 Chemical Structure| 113791-14-3

Structure of 113791-14-3

Chemical Structure| 113791-14-3

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Product Details of [ 113791-14-3 ]

CAS No. :113791-14-3
Formula : C5H10N2O3
M.W : 146.14
SMILES Code : O=C1NC[C@@H]1N.CC(O)=O

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Application In Synthesis of [ 113791-14-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 113791-14-3 ]

[ 113791-14-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 17945-79-8 ]
  • [ 1659-31-0 ]
  • [ 113791-14-3 ]
  • 4-(2-pyridyl)butyl N-[(3S)-2-oxoazetidin-3-yl]carbamate [ No CAS ]
YieldReaction ConditionsOperation in experiment
0.02 g General procedure: Under nitrogen atmosphere, to asuspension of 14-21 (1.0 eq.) in dry CH2Cl2 (2.0 mL), DIPEA (1.2 eq.) was added dropwise.Subsequently, the crude mixture containing the corresponding alkyl-2-oxopyridine-1-carboxylate (1.2eq.) in dry CH2Cl2 (4.0 mL) was added. The reaction mixture was stirred at room temperature for 16 h,diluted with CH2Cl2 (10 mL), washed with sat. NH4Cl solution (2 x 20mL), sat. NaHCO3 solution (2 x20 mL), and the organic layer dried over Na2SO4 and concentrated to dryness. Purification wasperformed either by typical silica gel flash chromatography or preparative HPLC affording the desired-lactam carbamates.
 

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