[ CAS No. 1147-43-9 ]

Name: 1147-43-9|2-(2-Aminobenzoyl)benzoic acid|95%
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SKU: A854195
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Quality Control of [ 1147-43-9 ]

COA NMR CNMR HPLC LC-MS

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SDS Specification

Alternatived Products of [ 1147-43-9 ]

Product Details of [ 1147-43-9 ]

CAS No. :	1147-43-9	MDL No. :	MFCD00007715
Formula :	C₁₄H₁₁NO₃	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	KORKIRUGUNPQML-UHFFFAOYSA-N
M.W :	241.24 g/mol	Pubchem ID :	70847
Synonyms :

Calculated chemistry of [ 1147-43-9 ]

Physicochemical Properties

Num. heavy atoms :	18
Num. arom. heavy atoms :	12
Fraction Csp3 :	0.0
Num. rotatable bonds :	3
Num. H-bond acceptors :	3.0
Num. H-bond donors :	2.0
Molar Refractivity :	67.68
TPSA :	80.39 Å²

Pharmacokinetics

GI absorption :	High
BBB permeant :	No
P-gp substrate :	No
CYP1A2 inhibitor :	No
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-6.11 cm/s

Lipophilicity

Log Po/w (iLOGP) :	1.05
Log Po/w (XLOGP3) :	2.34
Log Po/w (WLOGP) :	2.21
Log Po/w (MLOGP) :	1.87
Log Po/w (SILICOS-IT) :	2.07
Consensus Log Po/w :	1.91

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	0.0
Bioavailability Score :	0.56

Water Solubility

Log S (ESOL) :	-3.11
Solubility :	0.189 mg/ml ; 0.000785 mol/l
Class :	Soluble
Log S (Ali) :	-3.67
Solubility :	0.0519 mg/ml ; 0.000215 mol/l
Class :	Soluble
Log S (SILICOS-IT) :	-3.88
Solubility :	0.0315 mg/ml ; 0.000131 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	1.0 alert
Brenk :	1.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.95

Safety of [ 1147-43-9 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P261-P305+P351+P338	UN#:	N/A
Hazard Statements:	H315-H319-H335	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 1147-43-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 1147-43-9 ]
Downstream synthetic route of [ 1147-43-9 ]

[ 1147-43-9 ] Synthesis Path-Upstream 1~3

1
[ 1147-43-9 ]
[ 1143-50-6 ]

Reference： [1] Patent: US5869483, 1999, A,
[2] Patent: US5736538, 1998, A,
[3] Patent: US5739128, 1998, A,
[4] Patent: US5686445, 1997, A,
[5] Patent: US5512563, 1996, A,
[6] Patent: US5849735, 1998, A,
[7] Patent: US5693635, 1997, A,
[8] Patent: US5747487, 1998, A,
[9] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 11, p. 565

2
[ 1147-43-9 ]
[ 17356-08-0 ]
[ 1143-50-6 ]

Reference： [1] European Journal of Organic Chemistry, 2014, vol. 2014, # 34, p. 7664 - 7674

3
[ 1147-43-9 ]
[ 98-95-3 ]
[ 7732-18-5 ]
[ 1143-50-6 ]

Reference： [1] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 11, p. 565
[2] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 11, p. 565

[ 1147-43-9 ] Synthesis Path-Downstream 1~38

1
[ 64-17-5 ]
[ 1147-43-9 ]
2-anthraniloyl-benzoic acid ethyl ester [ No CAS ]

Reference： [1]Gazzetta Chimica Italiana,1933,vol. 63,p. 489,492

2
[ 1147-43-9 ]
[ 83132-81-4 ]

Reference： [1]Gazzetta Chimica Italiana,1933,vol. 63,p. 489,492
[2]Collection of Czechoslovak Chemical Communications,1982,vol. 47,p. 1746 - 1756

3
[ 1147-43-9 ]
[ 7265-24-9 ]
[ 612-34-0 ]

Reference： [1]Gazzetta Chimica Italiana,1953,vol. 83,p. 533,536

4
[ 1147-43-9 ]
[ 6079-73-8 ]
[ 1573-92-8 ]

Reference： [1]Chemische Berichte,1924,vol. 57,p. 317

5
[ 1147-43-9 ]
[ 1143-50-6 ]

Yield	Reaction Conditions	Operation in experiment
	In 5,5-dimethyl-1,3-cyclohexadiene;	REFERENCE EXAMPLE 92 5H-Dibenz[b,e]azepine-6,11-dione A mixture of 2.50 g of <strong>[1147-43-9]2-aminobenzophenone-2'-carboxylic acid</strong> in 50 ml of xylene is stirred at reflux for 23 hours. The mixture is filtered to give is 1.82 g of the desired product as a solid.
	In 5,5-dimethyl-1,3-cyclohexadiene;	REFERENCE EXAMPLE 92 5H-Dibenz[b,e]azepine-6,11-dione A mixture of 2.50 g of <strong>[1147-43-9]2-aminobenzophenone-2'-carboxylic acid</strong> in 50 ml of xylene is stirred at reflux for 23 hours. The mixture is filtered to give 1.82 g of the desired product as a solid.
	In 5,5-dimethyl-1,3-cyclohexadiene;	Reference Example 41 5H-Dibenz[b,e]azepine-6,11-dione A mixture of 2.50 g of <strong>[1147-43-9]2-aminobenzophenone-2'-carboxylic acid</strong> in 50 ml of xylene is stirred at reflux for 23 hours. The mixture is filtered to give 1.82 g of the desired product as a solid.

In 5,5-dimethyl-1,3-cyclohexadiene;

Reference Example 92 5H-Dibenz[b,e]azepine-6,11-dione A mixture of 2.50 g of <strong>[1147-43-9]2-aminobenzophenone-2'-carboxylic acid</strong> in 50 ml of xylene is stirred at reflux for 23 hours. The mixture is filtered to give 1.82 g of the desired product as a solid.

Reference： [1]Patent: US5869483,1999,A
[2]Patent: US5736538,1998,A
[3]Patent: US5849735,1998,A
[4]Patent: US5693635,1997,A
[5]Patent: DE258343,
Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 11,p. 565

6
[ 1147-43-9 ]
[ 486-25-9 ]
[ 6079-73-8 ]
[ 1573-92-8 ]
[ 84-65-1 ]

Reference： [1]Chemische Berichte,1924,vol. 57,p. 317

7
[ 1147-43-9 ]
[ 82-45-1 ]

Reference： [1]Patent: DE575580,1930,
Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 19,p. 1928
[2]Patent: DE575580,1930,
Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 19,p. 1928

8
[ 57901-53-8 ]
[ 1147-43-9 ]

Reference： [1]Patent: DE258343,
Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 11,p. 565

9
[ 1143-50-6 ]
furan-2,3,5(4H)-trione pyridine (1:1) [ No CAS ]
[ 1147-43-9 ]

Reference： [1]Chemische Berichte,1923,vol. 56,p. 22

10
[ 1147-43-9 ]
[ 57-13-6 ]
[ 16289-15-9 ]

Reference： [1]Gazzetta Chimica Italiana,1966,vol. 96,p. 1641 - 1647

11
[ 6629-04-5 ]
[ 1147-43-9 ]
[ 83132-66-5 ]

Reference： [1]Collection of Czechoslovak Chemical Communications,1982,vol. 47,p. 1746 - 1756

12
[ 1147-43-9 ]
[ 103222-66-8 ]
2-{2-[(R)-2-Amino-3-(1H-indol-3-yl)-propionylamino]-benzoyl}-benzoic acid; hydrochloride [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,1987,vol. 30,p. 1229 - 1239

13
[ 1143-50-6 ]
[ 1147-43-9 ]

Reference： [1]Collection of Czechoslovak Chemical Communications,1982,vol. 47,p. 1746 - 1756

14
[ 1147-43-9 ]
[ 74-89-5 ]
[ 85010-47-5 ]

Reference： [1]Canadian Journal of Chemistry,1983,vol. 61,p. 179 - 183

15
[ 1147-43-9 ]
[ 93-91-4 ]
[ 116690-83-6 ]

Reference： [1]Journal of Heterocyclic Chemistry,1987,vol. 24,p. 1733 - 1740

16
[ 1147-43-9 ]
[ 107-91-5 ]
[ 83132-70-1 ]

Reference： [1]Collection of Czechoslovak Chemical Communications,1982,vol. 47,p. 1746 - 1756

18
lactam of/the/ 2-<2-amino-benzoyl>-benzoic acid [ No CAS ]
[ 1147-43-9 ]

Reference： [1]Chemische Berichte,1923,vol. 56,p. 22

19
[ 1147-43-9 ]
[ 98-95-3 ]
[ 7732-18-5 ]
[ 1143-50-6 ]

Reference： [1]Patent: DE258343,
Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 11,p. 565

20
[ 1147-43-9 ]
[ 103343-29-9 ]

Reference： [1]Journal of Medicinal Chemistry,1987,vol. 30,p. 1229 - 1239

21
[ 1147-43-9 ]
[ 83132-74-5 ]

Reference： [1]Collection of Czechoslovak Chemical Communications,1982,vol. 47,p. 1746 - 1756

22
[ 1147-43-9 ]
[ 83132-78-9 ]

Reference： [1]Collection of Czechoslovak Chemical Communications,1982,vol. 47,p. 1746 - 1756

23
[ 1147-43-9 ]
[ 83143-33-3 ]

Reference： [1]Collection of Czechoslovak Chemical Communications,1982,vol. 47,p. 1746 - 1756

24
[ 1147-43-9 ]
[ 1151-04-8 ]

Reference： [1]Chemische Berichte,1924,vol. 57,p. 317

25
[ 110-89-4 ]
[ 1147-43-9 ]
[ 869937-11-1 ]

Reference： [1]Patent: EP1598343,2005,A1 .Location in patent: Page/Page column 57; 58

26
[ 1147-43-9 ]
[ 7732-18-5 ]
[ 814-68-6 ]
2-acrylaminobenzophenone-2'-carboxylic acid [ No CAS ]
[ 79-06-1 ]

Yield	Reaction Conditions	Operation in experiment
86%	With hydrogenchloride; sodium hydroxide; In ethanol;	EXAMPLE 1 Acrylamide of an Carboxy-Substituted Benzophenone 40 g (210 mmol) of <strong>[1147-43-9]2-aminobenzophenone-2'-carboxylic acid</strong> were dissolved in 500 ml of EtOH and 111 ml of 9.5 N NaOH (1.05 moles). 100 ml of H2 O were added, with stirring and cooling to 0-5 C., followed by 4.0 eq of acryloyl chloride. After completion and evaporation of EtOH, HCl was added to precipitate 2-acrylaminobenzophenone-2'-carboxylic acid (53 g, (86%), dry yield).

Reference： [1]Patent: US6123928,2000,A

27
triethyl-orthoacetate [ No CAS ]
[ 19614-14-3 ]
[ 1147-43-9 ]
[ 158425-08-2 ]

Yield	Reaction Conditions	Operation in experiment
	With hydrazine; In propionic acid anhydride;	EXAMPLE 199 3-Methyl-1-[2-[(1-oxopropyl)amino]phenyl]-4-(3-phenylpropyl)-1H-2,4-benzodiazepine (Formula I: R1, R4, R6 =H; R2 =(CH2)3Ph; R3 =Me; R5 = STR258 By a procedure analogous to that of Example 41, it is contemplated that 1-(2-aminophenyl)-4-(3-phenylpropyl)-3-methyl-1H-2,4-benzodiazepine can be synthesised from 2-(2-aminobenzoyl)-benzoic acid, hydrazine, bromobenzenepropane and triethyl-orthoacetate. It is further contemplated that this product may be acylated by treatment with propionic anhydride at room temperature to produce 3-methyl-1-[2-[(1-oxopropyl)amino]-phenyl]-4-(3-phenylpropyl)-1H-2,4-benzodiazepine.

Reference： [1]Patent: US5380721,1995,A

28
[ 1147-43-9 ]
[ 7732-18-5 ]
[ 814-68-6 ]
2-acrylaminobenzophenone-2'-carboxylic acid [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide; In ethanol;	Example 1 Synthesis of an Acrylamide Derivative of an Carboxy-Substituted Benzophenone 40 g (210 mmol) of <strong>[1147-43-9]2-aminobenzophenone-2'-carboxylic acid</strong> were placed in a L reaction flask followed by 500 ml of EtOH and 111 ml of 9.5N NaOH (1.05 moles). 100 ml of H2 O were added to dissolve sodium salts. With stirring and cooling to 0-5 C., 4.0 eq of acryloyl chloride were added over 10 minutes. The reaction was monitored by reverse phase HPLC. After completion, EtOH was removed by evaporation, and the reaction mixture acidified with HCl. A solid precipitated and was filtered. The yield of 2-acrylaminobenzophenone-2'-carboxylic acid was 53 g (86%).
	With sodium hydroxide; In ethanol;	Example 1 Synthesis of an Acrylamide Derivative of an Carboxy-Substituted Benzophenone 40 g (210 mmol) of <strong>[1147-43-9]2-aminobenzophenone-2'-carboxylic acid</strong> were placed in a L reaction flask followed by 500 ml of EtOH and 111 ml of 9.5 N NaOH (1.05 moles). 100 ml of H2 O were added to dissolve sodium salts. With stirring and cooling to 0-5 C., 4.0 eq of acryloyl chloride were added over 10 minutes. The reaction was monitored by reverse phase HPLC. After completion, EtOH was removed by evaporation, and the reaction mixture acidified with HCl. A solid precipitated and was filtered. The yield of 2-acrylaminobenzophenone-2'-carboxylic acid was 53 g (86%).

Reference： [1]Patent: US5487885,1996,A
[2]Patent: US5741924,1998,A

29
[ 75-09-2 ]
[ 1147-43-9 ]
[ 65947-75-3 ]
5-o-Carboxyphenyl-1,3-dihydro-3(R)-(3+-indolyl)methyl-2H-1,4-benzodiazepin-2-one [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	In tetrahydrofuran; methanol; chloroform methanol; chloroform; ethyl acetate;	EXAMPLE 58 5-o-Carboxyphenyl-1,3-dihydro-3(R)-(3+-indolyl)methyl-2H-1,4-benzodiazepin-2-one 2-Amino-2'-carboxybenzophenone (2.41 g, 10 mmol) was suspended in THF, CH2 Cl2, EtOAc and tryptophanyl chloride hydrochloride (2.59 g, 10 mmol) was added. The mixture was stirred at room temperature until reaction was complete by TLC. A solid was collected by filtration, dried, and dissolved in 40 ml of methanol. The pH of the solution was adjusted to a pH of 8-10 with 10% aqueous sodium hyroxide. After standing at room temperature for about 3 days, the solution was acidified to a pH of about 3. The solvent was evaporated and the residue was dissolved in 95/5 CHCl3 /CH3 OH and flash chromatographed on a silica gel 60 column with a 95:5 and 90:10 chloroform-methanol solvent system to give the title compound. HPLC: 96%. Elemental analysis calcd: C, 61.73; H, 3.97; N, 8.38 Found: C, 61.70; H, 4.09; N, 8.48.

Reference： [1]Patent: US4820834,1989,A

30
[ 1147-43-9 ]
[ 5543-24-8 ]

Yield	Reaction Conditions	Operation in experiment
	With hydrogenchloride; sodium chloride; sulfuric acid; sodium nitrite;copper(I) chloride; In water; ethyl acetate;	EXAMPLE 23 Preparation of 2-[2-(2-chlorobenzoyl)phenyl]-2-imidazoline To 250 ml. of concentrated sulfuric acid was added, with stirring and slight cooling, 37.5 g. (0.545 mole) of sodium nitrite. To this was added 120.5 g. (0.50 mole) of <strong>[1147-43-9]2-(2-aminobenzoyl)benzoic acid</strong> at such a rate that the temperature of the reaction mixture remained between 30-40. After the addition was complete the reaction mixture was stirred for one hour and then poured into one liter of ice and water and filtered. The filtrate was added rapidly to a stirred solution of 55 g. (0.555 mole) of cuprous chloride, 150 g. of sodium chloride, 250 ml. of concentrated hydrochloric acid and 300 ml. of water. The precipitated gum was extracted with chloroform and the extracts were washed twice with water, dried over anhydrous sodium sulfate and evaporated under vacuo to leave a red oil which crystallized upon scratching. Recrystallization from 200 ml. of ethyl acetate gave 2-(2-chlorobenzoyl)benzoic acid as a pink solid. A sample recrystallized three times from ethyl acetate gave colorless prisms, double m.p. 112-116 and 124-126. To a stirred suspension of 22.8 g. (0.60 mole) of lithium aluminum hydride in 700 ml. of dry tetrahydrofuran was added 104 g. (0.40 mole) of 2-(2-chlorobenzoyl)benzoic acid prepared as above in portions keeping the reaction mixture temperature between 15-30 with ice cooling.

Reference： [1]Patent: US3931217,1976,A

31
[ 194497-67-1 ]
[ 1147-43-9 ]
[ 91886-06-5 ]

Reference： [1]Inorganica Chimica Acta,1984,vol. 87,p. 35 - 40

32
[ 1147-43-9 ]
[ 62099-65-4 ]
[ 1352551-23-5 ]

Reference： [1]Molecules,2011,vol. 16,p. 8292 - 8304

33
[ 1147-43-9 ]
[ 17356-08-0 ]
C₁₅H₁₀N₂O₂ [ No CAS ]
[ 1143-50-6 ]

Reference： [1]European Journal of Organic Chemistry,2014,vol. 2014,p. 7664 - 7674

34
[ 10400-19-8 ]
[ 1147-43-9 ]
2-(2-[(pyridin-3-ylcarbonyl)amino]benzoyl)benzoic acid [ No CAS ]

Reference： [1]Journal of Enzyme Inhibition and Medicinal Chemistry,2016,vol. 31,p. 138 - 144

35
[ 189999-35-7 ]
[ 1147-43-9 ]
2′-iodo-[1,1′-biphenyl]-2-yl 2-(2-aminobenzoyl)benzoate [ No CAS ]

Reference： [1]Journal of Organic Chemistry,2017,vol. 82,p. 5250 - 5262
[2]Organic Letters,2017,vol. 19,p. 2600 - 2603

36
[ 189999-35-7 ]
[ 1147-43-9 ]
2'-((trimethylsilyl)ethynyl)-[1,1'-biphenyl]-2-yl-2-(2-aminobenzoyl)benzoate [ No CAS ]

Reference： [1]Organic Letters,2017,vol. 19,p. 2600 - 2603

37
[ 1147-43-9 ]
[ 578-95-0 ]

Yield	Reaction Conditions	Operation in experiment
75%	With 1,10-Phenanthroline; oxygen; copper diacetate; palladium diacetate; silver carbonate; In N,N-dimethyl-formamide; at 120℃; for 12h;	2- (2-aminobenzoyl) benzoic acid (120 mg, 0.5 mmol)Anhydrous 1,10-phenanthroline (18 mg, 0.1 mmol)Copper acetate (22.8 mg, 0.1 mmol)Palladium acetate (11.2 mg, 0.05 mmol)Silver carbonate (27.6 mg, 0.1 mmol),Anhydrous DMF 2 mL in 10 ml of the reactor,The mixture was stirred at 120 C for 12 h,After completion of the reaction, an appropriate amount of water (20 ml x 3) and ethyl acetate (20 ml)The organic phase was washed with saturated brine (20 ml), dried over anhydrous magnesium sulfate, concentrated,And purified by column chromatography on silica gel, using petroleum ether / ethyl acetate volume ratio of 1 ~ 3: 1 as the eluent,The eluate containing the target compound was collected, the solvent was evaporated and dried to give 70.4 mg of product 9 (10H) acridone in a yield of75%The product was a yellow solid.

Reference： [1]Patent: CN107162973,2017,A .Location in patent: Paragraph 0017; 0018; 0019

38
[ 14254-57-0 ]
[ 1147-43-9 ]
2-(2-[(pyridin-4-ylcarbonyl)amino]benzoyl)benzoic acid [ No CAS ]

Reference： [1]Archiv der Pharmazie,2017,vol. 350

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Ghs Precautionary Statements

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Code	Phrase
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P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
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Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 1147-43-9 ]

Quality Control of [ 1147-43-9 ]

Related Doc. of [ 1147-43-9 ]

Product Details of [ 1147-43-9 ]

Calculated chemistry of [ 1147-43-9 ]

Physicochemical Properties

Pharmacokinetics

Lipophilicity

Druglikeness

Water Solubility

Medicinal Chemistry

Safety of [ 1147-43-9 ]

Application In Synthesis of [ 1147-43-9 ]

[ 1147-43-9 ] Synthesis Path-Upstream 1~3

[ 1147-43-9 ] Synthesis Path-Downstream 1~38

Related Functional Groups of [ 1147-43-9 ]

Aryls

Ketones

Amines

Carboxylic Acids

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 1147-43-9 ]