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Chemical Structure| 1147081-43-3 Chemical Structure| 1147081-43-3

Structure of 1147081-43-3

Chemical Structure| 1147081-43-3

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Product Details of [ 1147081-43-3 ]

CAS No. :1147081-43-3
Formula : C27H17BrN2
M.W : 449.34
SMILES Code : BrC1=CC=C(C2=NC3=C4C=CC=CC4=C5C=CC=CC5=C3N2C6=CC=CC=C6)C=C1
MDL No. :N/A

Safety of [ 1147081-43-3 ]

Application In Synthesis of [ 1147081-43-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1147081-43-3 ]

[ 1147081-43-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 870119-58-7 ]
  • [ 1147081-43-3 ]
  • C45H29N3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
88% With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); In water; toluene; for 16h;Inert atmosphere; Reflux; In 100mL three-necked flask, were added M8 (3.54g, 9.6mmol), M1 (3.6g, 8mmol), potassium phosphate (5.1g, 24mmol), toluene 45mL, water 22mL, N2 replaced three times, then add S -phos (0.13g, 0.32mmol) and Pd2 (dba) 3 (0.07g, 0.08mmol).Replacement N2 and heated to reflux, and the reaction stopped after 16h.It cooled to room temperature, filtered to remove a small amount of black material was washed with toluene and methanol, i.e. a short column of silica gel to give a white solid 4.31g (HPLC: 99.8%), yield 88%,
 

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