[ CAS No. 1150561-61-7 ] {[proInfo.proName]}

Name: 1150561-61-7|2-Methoxy-3-(trifluoromethyl)pyridine-5-boronic Acid Pinacol Ester|98%
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Product Details of [ 1150561-61-7 ]

CAS No. :	1150561-61-7	MDL No. :	MFCD12026094
Formula :	C₁₃H₁₇BF₃NO₃	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	GNJXUHQYHOJYMP-UHFFFAOYSA-N
M.W :	303.09	Pubchem ID :	46739459
Synonyms :

Safety of [ 1150561-61-7 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P261-P305+P351+P338	UN#:	N/A
Hazard Statements:	H302-H315-H319-H335	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 1150561-61-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 1150561-61-7 ]

[ 1150561-61-7 ] Synthesis Path-Downstream 1~14

1
[ 1150561-61-7 ]
[ 1445651-35-3 ]
C₂₅H₂₆F₃N₃O₄ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate In water; acetonitrile at 125℃; for 0.25h; Microwave irradiation;	(S)-3-[4-(5-Chloro-6-methoxy-pyridin-3-yl)-quinolin-6-yloxy]-pyrrolidine-1-carboxylic acid tert-butyl ester General procedure: 3-chloro-2-methoxypyridine-5-boronic acid (CAS registry 942438-89-3) (57 mg, 0.30 mmol) followed by K3P04 (CAS registry 7778-53-2) (97.0 mg, 0.46 mmol), PdCI2(PPh3)2 (CAS registry 13965-03-2) (10.7 mg, 0.01 mmol) and finally water (0.2 ml) were added to a mixture of ((S)-3-(4-bromo-quinolin-6-yloxy)-pyrrolidine-1 -carboxylic acid tert-butyl ester (120 mg, 0.30 mmol) in acetonitrile (2 ml) in a microwave tube. The tube was capped and the reaction mixture was heated in a microwave reactor at 125°C for 15 min. The mixture was diluted with DCM and washed with sat. aq. NaHC03 soln. and the organic solution was separated through a phase separating cartridge affording a yellow solution. The crude product was purified by flash chromatography on silica gel (cyclohexane / EtOAc 100:0 to 0:100) to provide the title compound (1 14 mg, 82% yield). HPLC RtMO1=1.27 min; ESIMS: 456, 458 [(M+H)+].1H NMR (400 MHz, CDCI3): δ 8.80 (d, 1 H), 8.33 (d, 1 H), 8.16 (d, 1 H), 8.04 (d, 1 H), 7.49 (dd, 1 H), 7.46 (d, 1 H), 7.10 (br. s., 1 H) , 5.06 (m, 1 H), 4.03 (s, 3H), 3.57-3.36 (m, 4H), 2.10 (br. s., 2H ), 1.37 (d, 9H).

Reference： [1]Current Patent Assignee: Novartis (w/o Sandoz); NOVARTIS AG - WO2013/93850, 2013, A1 Location in patent: Page/Page column 60; 64

2
[ 1214377-42-0 ]
[ 73183-34-3 ]
[ 1150561-61-7 ]

Yield	Reaction Conditions	Operation in experiment
	With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 120℃; for 3h;Inert atmosphere;	<strong>[1214377-42-0]3-trifluoromethyl-2-methoxy-5-bromopyridine</strong> (0.50 g, 1.95 mmol)0.12 g (2.34 mmol) of diphenylolate borate,0.57 g (5.85 mmol) of potassium acetate and 0.10 g (0.14 mmol) of Pd (dppf) Cl2 in 100 mL eggplant vials, Adding dioxane 12mL, nitrogen protection, heating at 120 reflux 3h,To give the product containing 3- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -5-methanesulfonamido-6-methoxypyridine Of the reaction system, cooled to room temperature,To this system was added 0.37 g (1.63 mmol) of 2-amino-6-bromobenzothiazole,Potassium carbonate 0.67 g (4.88 mmol)Pd (dppf) Cl2 0.15 g (0.20 mmol) and water 3 mL,Nitrogen protection,120 heating reflux 6h,Cooled to room temperature, steamed to remove the solvent, silica gel column chromatography separation and purification,Eluent (V / V): chloroform / methanol = 50/1, gave 0.40 g of a white solid, yield: 75.43%

Reference： [1]Patent: CN106674200,2017,A .Location in patent: Paragraph 0099; 0100
[2]Bioorganic and Medicinal Chemistry,2019,vol. 27

3
[ 15864-32-1 ]
[ 1150561-61-7 ]
6-(5-trifluoromethyl-6-methoxy-3-pyridyl)-2-aminobenzothiazole [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
75.43%	With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate In water at 120℃; for 6h; Inert atmosphere;	18.1 (S) -N1- [6- (5-Trifluoromethyl-6-methoxy-3-pyridyl) -2-benzothiazolyl] -1,2-tetrahydropyrrole dicarboxamide (T18) synthesis 3-trifluoromethyl-2-methoxy-5-bromopyridine (0.50 g, 1.95 mmol)0.12 g (2.34 mmol) of diphenylolate borate,0.57 g (5.85 mmol) of potassium acetate and 0.10 g (0.14 mmol) of Pd (dppf) Cl2 in 100 mL eggplant vials, Adding dioxane 12mL, nitrogen protection, heating at 120 reflux 3h,To give the product containing 3- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -5-methanesulfonamido-6-methoxypyridine Of the reaction system, cooled to room temperature,To this system was added 0.37 g (1.63 mmol) of 2-amino-6-bromobenzothiazole,Potassium carbonate 0.67 g (4.88 mmol)Pd (dppf) Cl2 0.15 g (0.20 mmol) and water 3 mL,Nitrogen protection,120 heating reflux 6h,Cooled to room temperature, steamed to remove the solvent, silica gel column chromatography separation and purification,Eluent (V / V): chloroform / methanol = 50/1, gave 0.40 g of a white solid, yield: 75.43%

Reference： [1]Current Patent Assignee: XI AN JIAOTONG UNIVERSITY - CN106674200, 2017, A Location in patent: Paragraph 0101; 0102

4
[ 1150561-61-7 ]
(S)-N¹-[6-(5-trifluoromethyl-6-methoxy-3-pyridyl)-2-benzothiazolyl]-1,2-tetrahydropyrrole dicarboxamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / water / 6 h / 120 °C / Inert atmosphere 2.1: N,N-dimethyl-formamide / 24 h / 20 °C 2.2: 5 h / 20 °C

Reference： [1]Current Patent Assignee: XI AN JIAOTONG UNIVERSITY - CN106674200, 2017, A

5
[ 1150561-61-7 ]
C₂₀H₁₈F₃N₃O₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: bis-triphenylphosphine-palladium(II) chloride; potassium phosphate / water; acetonitrile / 0.25 h / 125 °C / Microwave irradiation 2: trifluoroacetic acid / dichloromethane / 18 h / 20 °C

Reference： [1]Current Patent Assignee: Novartis (w/o Sandoz); NOVARTIS AG - WO2013/93850, 2013, A1

6
[ 1150561-61-7 ]
[ 1445650-92-9 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 3 steps 1: bis-triphenylphosphine-palladium(II) chloride; potassium phosphate / water; acetonitrile / 0.25 h / 125 °C / Microwave irradiation 2: trifluoroacetic acid / dichloromethane / 18 h / 20 °C 3: N-[([(1E)-1-cyano-2-ethoxy-2-oxoethylidene]amino}oxy)(morpholin-4-yl)methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C

Reference： [1]Current Patent Assignee: Novartis (w/o Sandoz); NOVARTIS AG - WO2013/93850, 2013, A1

7
[ 1150561-61-7 ]
(S)-tert-butyl 3-((6-bromoquinazolin-4-yl)amino)piperidine-1-carboxylate [ No CAS ]
(S)-tert-butyl 3-((6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)quinazolin-4-yl)amino)piperidine-1-carboxylate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
81%	With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate In water Reflux; Inert atmosphere;	4.1.4 (S)-tert-Butyl 3-((6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)quinazolin-4-yl)amino)piperidine-1-carboxylate (12c) To a solution mixture of 11 (350mg, 0.86mmol) in DME/H2O (8mL/2mL), were added the 2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl) pyridine (561mg, 1.85mmol), PdCl2(dppf) (73.2mg, 0.1mmol) and Na2CO3 (182mg, 1.72mmol). The mixture was refluxed under N2 atmosphere for 4h and then the mixture was concentrated and purified by silica gel chromatography (CH2Cl2/CH3OH, 20:1) to give compound 12c (510mg, 81%) as a brown solid. MS (ESI) m/z: [M+H]+=504.2.

Reference： [1]Feng, Yifan; Duan, Weiming; Fan, Shu; Zhang, Hao; Zhang, San-Qi; Xin, Minhang [Bioorganic and Medicinal Chemistry, 2019, vol. 27, # 19]

8
[ 1150561-61-7 ]
C₂₄H₂₆F₃N₅O₃ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 3 steps 1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water / Reflux; Inert atmosphere 2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C 3: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / dichloromethane / 20 °C

Reference： [1]Feng, Yifan; Duan, Weiming; Fan, Shu; Zhang, Hao; Zhang, San-Qi; Xin, Minhang [Bioorganic and Medicinal Chemistry, 2019, vol. 27, # 19]

9
[ 1150561-61-7 ]
C₂₀H₂₀F₃N₅O [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water / Reflux; Inert atmosphere 2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

Reference： [1]Feng, Yifan; Duan, Weiming; Fan, Shu; Zhang, Hao; Zhang, San-Qi; Xin, Minhang [Bioorganic and Medicinal Chemistry, 2019, vol. 27, # 19]

10
[ 1150561-61-7 ]
(S)-2-((6-bromoquinazolin-4-yl)amino)-1-(4-methylpiperazin-1-yl)propan-1-one [ No CAS ]
(S)-2-((6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)quinazolin-4-yl)amino)-1-(4-methylpiperazin-1-yl)propan-1-one [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
47.7%	With palladium (II) [1,1'-bis(diphenylphosphanyl)ferrocene] dichloride; anhydrous sodium carbonate In 1,2-dimethoxyethane; lithium hydroxide monohydrate for 2.5h; Reflux; Inert atmosphere;	14 (S)-N-butyl-2-((6-(6-methoxypyridin-3-yl)quinazolin-4-yl)amino)propanamide (Compound 1) General procedure: Take the intermediate (S)-2-((6-bromo-4-quinazolinyl)amino)-N-butylpropionamide (280 mL, 0.80 mmol), 2-methoxy-5-pyridineboronic acid (184 mg , 1.20 mmol), Na2CO3 (170 mg, 1.60 mmol), PdCl2(dppf) (71 mg, 0.097 mmol), ethylene glycol dimethyl ether (8 mL) and H2O (2 mL) N2 protection, heated to reflux for about 2.5 h, TLC showed The reaction is complete. After cooling, evaporation to dryness under reduced pressure was performed by column chromatography to obtain 65 mg of a white solid with a yield of 63.4%.

Reference： [1]Current Patent Assignee: XIANGSAN TRAFFIC UNIV - CN114292259, 2022, A Location in patent: Paragraph 0045-0047; 0050-0051; 0103-0104; 0107-0108; ...

11
[ 1150561-61-7 ]
C₁₆H₂₁ClN₆O [ No CAS ]
(S)-2-((6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)pyrido[3,2-d]pyrimidin-4-yl)amino)-1-(4-methylpiperazin-1-yl)butanone [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
33.4%	With palladium (II) [1,1'-bis(diphenylphosphanyl)ferrocene] dichloride; anhydrous sodium carbonate In 1,2-dimethoxyethane; lithium hydroxide monohydrate for 2.5h; Reflux;	24 (S)-N-butyl-2-((6-(6-methoxypyridin-3-yl)quinazolin-4-yl)amino)propanamide (Compound 1) General procedure: Take the intermediate (S)-2-((6-bromo-4-quinazolinyl)amino)-N-butylpropionamide (280 mL, 0.80 mmol), 2-methoxy-5-pyridineboronic acid (184 mg , 1.20 mmol), Na2CO3 (170 mg, 1.60 mmol), PdCl2(dppf) (71 mg, 0.097 mmol), ethylene glycol dimethyl ether (8 mL) and H2O (2 mL) N2 protection, heated to reflux for about 2.5 h, TLC showed The reaction is complete. After cooling, evaporation to dryness under reduced pressure was performed by column chromatography to obtain 65 mg of a white solid with a yield of 63.4%.

Reference： [1]Current Patent Assignee: XIANGSAN TRAFFIC UNIV - CN114292259, 2022, A Location in patent: Paragraph 0045-0047; 0050-0051; 0103-0104; 0107-0108; ...

12
[ 1150561-61-7 ]
C₁₅H₁₉ClN₆O [ No CAS ]
(S)-2-((6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)pyrido[3,2-d]pyrimidin-4-yl)amino)-1-(4-methylpiperazin-1-yl)propan-1-one [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
50.5%	With palladium (II) [1,1'-bis(diphenylphosphanyl)ferrocene] dichloride; anhydrous sodium carbonate In 1,2-dimethoxyethane; lithium hydroxide monohydrate for 2.5h; Reflux; Inert atmosphere;	22 (S)-N-butyl-2-((6-(6-methoxypyridin-3-yl)quinazolin-4-yl)amino)propanamide (Compound 1) General procedure: Take the intermediate (S)-2-((6-bromo-4-quinazolinyl)amino)-N-butylpropionamide (280 mL, 0.80 mmol), 2-methoxy-5-pyridineboronic acid (184 mg , 1.20 mmol), Na2CO3 (170 mg, 1.60 mmol), PdCl2(dppf) (71 mg, 0.097 mmol), ethylene glycol dimethyl ether (8 mL) and H2O (2 mL) N2 protection, heated to reflux for about 2.5 h, TLC showed The reaction is complete. After cooling, evaporation to dryness under reduced pressure was performed by column chromatography to obtain 65 mg of a white solid with a yield of 63.4%.

Reference： [1]Current Patent Assignee: XIANGSAN TRAFFIC UNIV - CN114292259, 2022, A Location in patent: Paragraph 0045-0047; 0050-0051; 0103-0104; 0107-0108; ...

13
[ 1150561-61-7 ]
(S)-1-(3-((6-bromothieno[2,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one [ No CAS ]
(S)-1-(3-((6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)thieno-[2,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
75%	With palladium (II) [1,1'-bis(diphenylphosphanyl)ferrocene] dichloride; potassium carbonate In 1,4-dioxane; lithium hydroxide monohydrate at 100℃; for 5h; Inert atmosphere;

Reference： [1]Zhang, Jingbo; Jiang, Huimin; Lin, Songwen; Wu, Deyu; Tian, Hua; Jiang, Lin; Cui, Yiman; Jin, Jing; Chen, Xiaoguang; Xu, Heng [Journal of Medicinal Chemistry, 2022, vol. 65, # 11, p. 8011 - 8028]

14
[ 1150561-61-7 ]
(S)-1-(3-((6-bromothieno[2,3-d]pyrimidin-4-yl)oxy)pyrrolidin-1-yl)propan-1-one [ No CAS ]
(S)-1-(3-((6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)thieno-[2,3-d]pyrimidin-4-yl)oxy)pyrrolidin-1-yl)propan-1-one [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
58%	With palladium (II) [1,1'-bis(diphenylphosphanyl)ferrocene] dichloride; potassium carbonate In 1,4-dioxane; lithium hydroxide monohydrate at 100℃; for 5h; Inert atmosphere;

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P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
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Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 1150561-61-7 ] {[proInfo.proName]}

Quality Control of [ 1150561-61-7 ]

Related Doc. of [ 1150561-61-7 ]

Product Details of [ 1150561-61-7 ]

Safety of [ 1150561-61-7 ]

Application In Synthesis of [ 1150561-61-7 ]

[ 1150561-61-7 ] Synthesis Path-Downstream 1~14

Related Functional Groups of [ 1150561-61-7 ]

Fluorinated Building Blocks

Organoboron

Ethers

Esters

Trifluoromethyls

Related Parent Nucleus of [ 1150561-61-7 ]

Pyridines

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 1150561-61-7 ]

Related Parent Nucleus of
[ 1150561-61-7 ]