Home Cart Sign in  
Chemical Structure| 1152110-85-4 Chemical Structure| 1152110-85-4

Structure of 1152110-85-4

Chemical Structure| 1152110-85-4

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1152110-85-4 ]

CAS No. :1152110-85-4
Formula : C6H12ClNO
M.W : 149.62
SMILES Code : OC1CNCC21CC2.[H]Cl
MDL No. :MFCD19690570

Safety of [ 1152110-85-4 ]

Application In Synthesis of [ 1152110-85-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1152110-85-4 ]

[ 1152110-85-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 105806-13-1 ]
  • [ 1152110-85-4 ]
  • [ 1152110-86-5 ]
YieldReaction ConditionsOperation in experiment
51% Part E: 5-(5-Fluoro-6-hydrazino-2-methyl-4-pyrimidinyl)-5-azaspiro[2.4]heptan-7-ol. 4,6-Dichloro-5-fluoro-2-methylpyrimidine (110 mg, 0.636 mmol) was dissolved in 3 ml. of MeOH then added 5-azaspiro[2.4]heptan-7-ol hydrochloride (685 mg, 0.668 mmol) was added, followed by DIPEA (243 mul_, 1.4 mmol). The resulting reaction mixture was microwaved at 120 0C for 30 min, the voliailes were concentrated in vacuo, and the residue was dissolved in a mixture of DMSO (4 ml.) and MeOH (1 ml_). Then hydrazine monohydrate was added (600 mul_), and the contents were heated to 60 0C overnight. The reaction mixture was then cooled to room temperature and purified by RP-HPLC to provide 5-(5-fluoro-6-hydrazino-2-methyl-4-pyrimidinyl)-5-azaspiro[2.4]heptan-7-ol (82 mg, 51%). LCMS: (M+H)+: 254.
 

Historical Records