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Chemical Structure| 115269-99-3 Chemical Structure| 115269-99-3

Structure of 115269-99-3

Chemical Structure| 115269-99-3

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Product Details of [ 115269-99-3 ]

CAS No. :115269-99-3
Formula : C13H23NO4
M.W : 257.33
SMILES Code : C=CCN(C(OC(C)(C)C)=O)C(OC(C)(C)C)=O
MDL No. :MFCD04115302

Safety of [ 115269-99-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

Application In Synthesis of [ 115269-99-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 115269-99-3 ]

[ 115269-99-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 570-02-5 ]
  • [ 115269-99-3 ]
  • (E)-N,N-bis(tert-butoxycarbonyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-amine [ No CAS ]
YieldReaction ConditionsOperation in experiment
93% With palladium(II) trifluoroacetate; silver carbonate; In tetrahydrofuran; dimethyl sulfoxide; at 100℃; for 8h;Inert atmosphere; General procedure: To an oven-dried pressure tube were sequentially added aryl carboxylic acid 1 (0.2 mmol), olefin 2 (0.24 mmol), Pd(TFA)2 (3.33 mg, 5.0 mol%), Ag2CO3 (55.2 mg, 0.2 mmol), THF (2.0 mL) and DMSO (0.10 mL) under nitrogen at room temperature. After degassing three times, the reaction mixture was heated at 100 C for 8 h, and then was cooled to room temperature. Water (20.0 mL)was added, and the mixture was extracted with ethyl acetate (3 5.0 mL). The combined organic layer was washed with brine, dried over anhydrious Na2SO4, filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluant: hexane/ethyl acetate) to give the pure target product.
 

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