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CAS No. : | 115913-30-9 | MDL No. : | MFCD23164149 |
Formula : | C9H12O2 | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | VBZKYGFCGJCPCT-UHFFFAOYSA-N |
M.W : | 152.19 | Pubchem ID : | 11159413 |
Synonyms : |
|
Signal Word: | Warning | Class: | N/A |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H302-H315-H319 | Packing Group: | N/A |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
50% | With sodium hypochlorite In 1,4-dioxane at 10 - 15℃; for 4 h; | Compound 4 (23 g) was dissolved in dioxane (100 mL)And then added dropwise to sodium hypochlorite solution (1 L) at 10 ° C to 15 ° C,Stirring was continued for 4 hours,Then sodium thiosulfate (6 g) was added.The reaction was washed with chloroform (400 mL x 3). The aqueous phase was acidified to pH <1 with concentrated hydrochloric acid, followed by extraction with ethyl acetate (500 mL x 3). The combined extracts of ethyl acetate were washed with Baisha brine, dried over anhydrous sodium sulfate and concentrated by filtration to give compound 5 (11.5 g) in 50percent yield. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
23 g | at 15 - 25℃; for 16 h; Irradiation | To the solution of the obtained compound 2 was added diacetyl (35 mL)Control the temperature at 15 ° C to 25 ° C,In the 80W to 150W medium pressure mercury lamp irradiation reaction 16 hours.The reaction system was concentrated directly to give the crude product,Recrystallization from n-hexane gave pure product of compound 4 (23 g) in 43percent yield. |
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