630-580-1088 sales@ambeed.com
Structure Search

List Search MOL Search Structure Search

0
Chemistry
Boronic acids/esters >>1,3,2-DioxaborinaneAliphatic BoronsAromatic BoronsBCATBoric AcidsMIDA BoronatesOther BoronatesOther BoronsOxaborolesCatalysis Chemistry >>Achiral Crown LigandsC-H ActivationCarbon-Donor LigandsChiral Carbon LigandsChiral Crown LigandsChiral Olefin LigandsCross-CouplingCross-Coupling Using Transition Metal CatalystsDACH or Trost LigandsChemical Biology >>Conjugation Chemistry
GlycoscienceLinkers and CrosslinkersNucleic Acid ChemistryPEGylationPeptide ChemistryPhotolabile Protecting GroupHeterocyclic Building Blocks >>AcridinesAliphatic HeterocyclesAromatic HeterocyclesAzetidinesBenzimidazolesBenzisoxazolesBenzodioxansBenzofuransBenzothiazolesInorganic reagents >>Inorganic ReagentOrganic Building Blocks >>Acid AnhydridesAcyl ChloridesAlcohols
AldehydesAliphatic Chain HydrocarbonsAliphatic Cyclic HydrocarbonsAlkenesAlkylsAlkynesOrganometallic Reagents >>Grignard ReagentsOrganoarsenicOrganobismuthOrganoboronOrganogermaniumOrganolithiumOrganomercuryOrganosiliconOrganotinSpecialty Synthesis >>Enzyme-Mediated SynthesisFluorous SynthesisIonic LiquidsSolid Supported SynthesisStains and Dyes >>
Acid DyesAzoic DyesBasic DyesDirect DyesDisperse DyesDye IntermediatesMordant DyesOil DyesOther Stains and DyesSynthetic Reagents >>Acids and BasesC-C Bond FormationC-X Bond Formation (Halogen)C-X Bond Formation (Non-Halogen)Chelation and Complexation CompoundsCondensation AgentsCouplingDehydrating ReagentsFluorination Reagent
Pharmaceutical Intermediates
Analgesics >>BenzhydrocodoneBicifadineCapsaicinCelecoxibDebio-0827DexamethasoneElagolix SodiumEsketamine HydrochlorideIbuprofen SodiumAnesthetics >>CiprofolEsketamine HydrochlorideFospropofol Fospropofol DisodiumLevobupivacaine RemimazolamRemimazolam BesilateRemimazolam BesylateRopivacaineAnti-Addiction Agents >>Kakonein
Lofexidine HydrochlorideVarenicline Anti-inflammatory Agents >>ApremilastAsunaprevirATB-346 RelatedBalsalazide BaricitinibBencycloquidium BromideBudesonideCefiderocol Sulfate TosylateCeftaroline Fosamil AcetateAntibacterials >>AFN-1252 RelatedAlatrofloxacin Bedaquiline FumarateBesifloxacin BrilacidinCaspofungin AcetateCefiderocol Sulfate TosylateCefilavancinCeftaroline Fosamil
Anticonvulsants >>BrivaracetamCannabidiolEscitalopram OxalateEslicarbazepine Acetate RelatedFosphenytoinGabapentin EnacarbilJNJ-10234094LacosamideLevetiracetam RelatedAntidementia Agents >>Azeliragon RelatedDavunetideDonepezil HydrochlorideDonepezil RelatedEnsaculinFlorbetaben Flortaucipir F 18Flutemetamol IdalopirdineAntidepressants >>4-Chlorokynurenine
AgomelatineAgomelatine RelatedAllopregnanolone RelatedAmibegronAmitifadineAripiprazole RelatedBasimglurantBefloxatoneAntiemetics >>AprepitantAprepitant RelatedDolasetron RelatedDolasetron Mesylate HydrateFosaprepitant DimeglumineFosaprepitant RelatedOlanzapinePalonosetron RelatedPalonosetron HydrochlorideAntifungals >>Anidulafungin RelatedCabotegravirMore >>
Inhibitors/Agonists
ADC >>ADC AntibodyADC LinkerADC Linker with PayloadADC ToxinAntibody-Drug Conjugates (ADCs)Drug-Linker Conjugates for ADCAngiogenesis >>ALKBcr-AblBTKEGFRFAKFGFRFLT3HER2HIFAnti-infection >>3CLproAntibacterialAntibioticAntifungal
AntiparasiticAntiprotozoalAntiviralArenavirusBVDVApoptosis >>Apoptosis InducerBcl-2Bcl-6BRKc-Mycc-RETC/EBPCARDCaspaseAutophagy >>Atg4ATG4BATTECsAUTACsAutophagyBeclin1
FKBPLC3LRRK2Biochemical Reagent >>Cell Cycle >>AntifolateAPCAurora KinaseBUBCasein KinaseCdc25CDKChkCRISPR/Cas9Cytoskeleton >>ActinArp2/3 ComplexCYTHCytoplasmic DyneinDynaminFAKMore >>
Material Science
Aggregation-Induced Emission >>Other AIE BlocksTetraphenylethylene SeriesCOFs Linkers >>Aldehyde COFs LinkersAlkynyl COFs LinkersAmine COFs LinkersBoric COFs LinkersCyano COFs LinkersMultifunctional COFs linkersOther COFs linkersTriptycene SeriesElectronic Materials >>Battery MaterialsDye-Sensitized Solar Cell (DSSC) MaterialsElectronic MaterialLiquid Crystal (LC) MaterialsMolecular ConductorsOrganic Light-Emitting Diode (OLED) MaterialsOrganic Solar Cell (OPV) MaterialsOrganic Transistor (OFET) MaterialsPerovskite Solar Cell (PSC) MaterialsMagnetic Materials >>Magnetic Ionic LiquidsMagnetic MaterialMagnetic Metal Complexes
Organic Radicals Material Chemical Compounds >>Ligands for Functional Metal ComplexesLiquid Crystal (LC) Building BlocksPhthalocyanine Building BlocksPolymer and Macromolecule Semiconductor Building BlocksSmall Molecule Semiconductor Building BlocksSolubility Enhancing Reagents Supramolecular Host Materials MOF Ligands >>Carboxylic Acid MOF LigandsCarboxylic Acid Nitrogen-Containing Mixed MOF LigandsNitrogen-Containing MOF LigandsOther MOF LigandsNanomaterials >>Carbon NanomaterialsCeramic MembranesDendrimersGold NanoparticlesIron Oxide NanoparticlesMaterials by ApplicationMesoporous MaterialsMetals and Metal AlloysNano Minerals: NanoclaysOLED Materials >>Dopant
HostHTMOLED IntermediatesOther OLED related materialsOptical Materials >>Coumarin DyesCyanine and Squarylium DyesDCM DyesDipyrromethene DyesFluorescence MaterialsFluorescent ProbesHeat and Pressure Sensitive DyesNear-Infrared (NIR) DyesOrganic Non-Linear Optical (NLO) MaterialsOrganic Pigments >>Organic PigmentOther Materials >>Material OtherPolymer Science >>MonomersPolymer AdditivesPolymerization ReagentsPolymersResins
Contact Us
Home Cart 0 Sign in  
X
Chemistry
Organic Building Blocks
Aryls
3-methyl-1,1'-biphenyl
3,4'-Dimethyl-[1,1'-biphenyl]-4-amine
Chemistry
Organic Building Blocks
Aryls
Benzene Compounds
3-methyl-1,1'-biphenyl
biphenyl

[ CAS No. 116668-37-2 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
3d Animation Molecule Structure of 116668-37-2
Chemical Structure| 116668-37-2
Chemical Structure| 116668-37-2
Structure of 116668-37-2 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

For Research Only 120K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 116668-37-2 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 116668-37-2 ]

SDS Specification
Alternatived Products of [ 116668-37-2 ]
Product Citations

Product Details of [ 116668-37-2 ]

CAS No. :116668-37-2 MDL No. :MFCD08701580
Formula : C14H15N Boiling Point : -
Linear Structure Formula :- InChI Key :RHFXTYPJXCHYIG-UHFFFAOYSA-N
M.W : 197.28 Pubchem ID :23005184
Synonyms :

Safety of [ 116668-37-2 ]

Signal Word:Warning Class:
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 UN#:
Hazard Statements:H315-H319 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 116668-37-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 116668-37-2 ]

[ 116668-37-2 ] Synthesis Path-Downstream   1~13

  • 1
  • [ 88-72-2 ]
  • [ 116668-37-2 ]
YieldReaction ConditionsOperation in experiment
With aluminium trichloride; toluene
Reference： [1]Kliegl; Huber [Chemische Berichte, 1920, vol. 53, p. 1655]
  • 2
  • [ 872275-92-8 ]
  • [ 116668-37-2 ]
Reference： [1]Current Patent Assignee: I.G. FARBENINDUSTRIE AG (historic) - DE582844, 1931, C [Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 20, p. 449][Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 20, p. 449]
  • 3
  • [ 116668-37-2 ]
  • [ 108-24-7 ]
  • [ 872275-92-8 ]
Reference： [1]Kliegl; Huber [Chemische Berichte, 1920, vol. 53, p. 1655]
  • 4
  • [ 7446-70-0 ]
  • [ 88-72-2 ]
  • [ 108-88-3 ]
  • [ 116668-37-2 ]
Reference： [1]Kliegl; Huber [Chemische Berichte, 1920, vol. 53, p. 1655]
  • 6
  • [ 116668-37-2 ]
  • [ 1266338-73-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: dichloromethane / 20 °C 2: palladium diacetate; sodium hydrogencarbonate / 1,2-dichloro-ethane / 3 h / 80 °C
Reference： [1]Sun, Kai; Li, Yan; Xiong, Tao; Zhang, Jingping; Zhang, Qian [Journal of the American Chemical Society, 2011, vol. 133, # 6, p. 1694 - 1697]
  • 7
  • [ 116668-37-2 ]
  • [ 75-36-5 ]
  • [ 872275-92-8 ]
YieldReaction ConditionsOperation in experiment
In dichloromethane at 20℃;
Reference： [1]Sun, Kai; Li, Yan; Xiong, Tao; Zhang, Jingping; Zhang, Qian [Journal of the American Chemical Society, 2011, vol. 133, # 6, p. 1694 - 1697]
  • 8
  • [ 116668-37-2 ]
  • 4-methyl-2-(4'-methylphenyl)-5-methylphenanthridin-5-ium chloride [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 4 steps 1.1: triethylamine / dichloromethane / 4 h / 20 °C 2.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere 2.2: 4 h / 0 - 20 °C / Inert atmosphere 3.1: sodium carbonate; palladium diacetate; triphenylphosphine / N,N-dimethyl-formamide / 5 h / 155 °C / Inert atmosphere 4.1: diisobutylaluminium hydride / tetrahydrofuran; toluene / -10 - 20 °C / Inert atmosphere
Reference： [1]Liu, Jingru; Ma, Ruxin; Bi, Fangchao; Zhang, Fa; Hu, Chaoyu; Venter, Henrietta; Semple, Susan J.; Ma, Shutao [Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 10, p. 1825 - 1831]
  • 9
  • [ 116668-37-2 ]
  • C22H19NO [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1.1: triethylamine / dichloromethane / 4 h / 20 °C 2.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere 2.2: 4 h / 0 - 20 °C / Inert atmosphere 3.1: sodium carbonate; palladium diacetate; triphenylphosphine / N,N-dimethyl-formamide / 5 h / 155 °C / Inert atmosphere
Reference： [1]Liu, Jingru; Ma, Ruxin; Bi, Fangchao; Zhang, Fa; Hu, Chaoyu; Venter, Henrietta; Semple, Susan J.; Ma, Shutao [Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 10, p. 1825 - 1831]
  • 10
  • [ 116668-37-2 ]
  • C22H20BrNO [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1.1: triethylamine / dichloromethane / 4 h / 20 °C 2.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere 2.2: 4 h / 0 - 20 °C / Inert atmosphere
Reference： [1]Liu, Jingru; Ma, Ruxin; Bi, Fangchao; Zhang, Fa; Hu, Chaoyu; Venter, Henrietta; Semple, Susan J.; Ma, Shutao [Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 10, p. 1825 - 1831]
  • 11
  • [ 116668-37-2 ]
  • [ 7154-66-7 ]
  • C21H18BrNO [ No CAS ]
YieldReaction ConditionsOperation in experiment
With triethylamine In dichloromethane at 20℃; for 4h; 2. Benzamides 4a-x General procedure: The 2-Bromobenzoic acid (5.7 mmol) was refluxed in SOCl2 (13 mmol) at 78 for 2 h and then superfluous SOCl2 was removed under reduced pressure. The reaction solution was diluted with dichloromethane and added dropwise to a solution of 3a-x (5.2 mmol) and triethylamine (2.25 mL). The reaction was carried out at room temperature for 4 h (TLC monitored the reaction). The reaction mixture was concentrated under reduced pressure to remove excess dichloromethane. The residue was added an appropriate amount of dichloromethane/petroleum ether (1:10), filtered, and dried to give white or faint yellow solids of benzamides 4a-x, yield: 60-98% in two steps.
Reference： [1]Liu, Jingru; Ma, Ruxin; Bi, Fangchao; Zhang, Fa; Hu, Chaoyu; Venter, Henrietta; Semple, Susan J.; Ma, Shutao [Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 10, p. 1825 - 1831]
  • 12
  • [ 5720-05-8 ]
  • [ 583-75-5 ]
  • [ 116668-37-2 ]
YieldReaction ConditionsOperation in experiment
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In water; N,N-dimethyl-formamide at 100℃; for 15h; Inert atmosphere; 1. 1,1'-Biphenyl-4-amines 3a-x General procedure: 4-Bromobenzenamines 1a-c (6.4 mmol) were dissolved in the mixed solvents (2M K2CO3:DMF = 1:1, 24 mL), and then added corresponding 4-substituent phenylboronic acids 2a-h (7.7 mmol) and Pd (PPh3)4 (0.22 mmol) under argon. The reaction mixture was refluxed at 100 for 15 h (TLC monitored the reaction). The reaction was then cooled to room temperature and filtered. The filtrate was added 10 times the amount of water and extracted with ethyl acetate. The organic layer was washed with saturated NaCl solution, concentrated under reduced pressure, and dried to give a crude product. The crude product was purified by flash column chromatography (ethyl acetate/petroleum ether, 1:8-1:5) to afford 1,1'-biphenyl-4-amines 3a-x, yield: 77-95%.
Reference： [1]Liu, Jingru; Ma, Ruxin; Bi, Fangchao; Zhang, Fa; Hu, Chaoyu; Venter, Henrietta; Semple, Susan J.; Ma, Shutao [Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 10, p. 1825 - 1831]
  • 13
  • [ 5152-76-1 ]
  • [ 108-88-3 ]
  • [ 116668-37-2 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: aluminium trichloride
Reference： [1]Current Patent Assignee: I.G. FARBENINDUSTRIE AG (historic) - DE582844, 1931, C [Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 20, p. 449][Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 20, p. 449]

Tags: 116668-37-2 synthesis path| 116668-37-2 SDS| 116668-37-2 COA| 116668-37-2 purity| 116668-37-2 application| 116668-37-2 NMR| 116668-37-2 COA| 116668-37-2 structure

Recommend Products
Same Skeleton Products
Related Products
Isomers
Categories
Chemistry
Organic Building Blocks
Aryls
3-methyl-1,1'-biphenyl
Chemistry
Organic Building Blocks
Benzene Compounds
biphenyl

Technical Information

• Benzylic Oxidation • Birch Reduction • Birch Reduction of Benzene • Blanc Chloromethylation • Complete Benzylic Oxidations of Alkyl Chains • Complete Benzylic Oxidations of Alkyl Chains • Conversion of Amino with Nitro • Deprotonation of Methylbenzene • Directing Electron-Donating Effects of Alkyl • Electrophilic Chloromethylation of Polystyrene • Friedel-Crafts Alkylation of Benzene with Acyl Chlorides • Friedel-Crafts Alkylation of Benzene with Carboxylic Anhydrides • Friedel-Crafts Alkylation Using Alkenes • Friedel-Crafts Alkylations of Benzene Using Alkenes • Friedel-Crafts Alkylations Using Alcohols • Friedel-Crafts Reaction • Groups that Withdraw Electrons Inductively Are Deactivating and Meta Directing • Halogenation of Benzene • Hydrogenation to Cyclohexane • Hydrogenolysis of Benzyl Ether • Nitration of Benzene • Nucleophilic Aromatic Substitution • Nucleophilic Aromatic Substitution with Amine • Oxidation of Alkyl-substituted Benzenes Gives Aromatic Ketones • Preparation of Alkylbenzene • Reactions of Benzene and Substituted Benzenes • Reductive Removal of a Diazonium Group • Reverse Sulfonation——Hydrolysis • Sulfonation of Benzene • The Acylium Ion Attack Benzene to Form Phenyl Ketones • The Claisen Rearrangement • The Nitro Group Conver to the Amino Function • Vilsmeier-Haack Reaction
Historical Records
; ;