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Chemical Structure| 117755-95-0 Chemical Structure| 117755-95-0

Structure of 117755-95-0

Chemical Structure| 117755-95-0

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Product Details of [ 117755-95-0 ]

CAS No. :117755-95-0
Formula : C11H15NO2
M.W : 193.24
SMILES Code : CC(NC1=CC=CC=C1C)(C)C(O)=O
MDL No. :MFCD04116936

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Application In Synthesis of [ 117755-95-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 117755-95-0 ]

[ 117755-95-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 117755-95-0 ]
  • [ 62058-03-1 ]
  • C21H30N2O2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
44% Example B.11 Preparation of compound 34; To a mixture of 2-methyl-iV-o-tolyl-alanine [117755-95-0] (0.006 mol), EDCI (0.009 mol), HOBt (0.009 mol), NMM (0.024 mol) and CH2Cl2 (80 ml), a solution of (lalpha,3alpha,4alpha,5beta,7alpha)-4-amino-tricyclo[3.3.1.13'7]decan-l-ol [62058-03-1] (0.006 mol) in DMF (20 ml) was added after 10 minutes. The reaction mixture was stirred for 16 hours at 20°C under N2 flow. The mixture was poured out into a column comprising diatomaceous earth. Then the column was washed with CH3OH/CH2C12 5/95. The filtrate was purified by flash chromatography (eluent: CH3OH(2-3percent)/CH2Cl2) over SiO2, yielding 0.89 g (44percent) of compound 34
 

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