Home Cart 0 Sign in  

[ CAS No. 1184259-08-2 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 1184259-08-2
Chemical Structure| 1184259-08-2
Structure of 1184259-08-2 * Storage: {[proInfo.prStorage]}

Quality Control of [ 1184259-08-2 ]

Related Doc. of [ 1184259-08-2 ]

SDS
Alternatived Products of [ 1184259-08-2 ]
Alternatived Products of [ 1184259-08-2 ]

Product Details of [ 1184259-08-2 ]

CAS No. :1184259-08-2 MDL No. :MFCD22493666
Formula : C13H16BNO5 Boiling Point : -
Linear Structure Formula :- InChI Key :N/A
M.W :277.08 g/mol Pubchem ID :-
Synonyms :

Safety of [ 1184259-08-2 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1184259-08-2 ]

  • Downstream synthetic route of [ 1184259-08-2 ]

[ 1184259-08-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5551-12-2 ]
  • [ 73183-34-3 ]
  • [ 1184259-08-2 ]
YieldReaction ConditionsOperation in experiment
With potassium acetate;tris-(dibenzylideneacetone)dipalladium(0); tricyclohexylphosphine; In 1,4-dioxane; at 80℃; for 16.5h; Example 87; 2-Nitro-5-(4A5,5-tetramethvl-ri.3.21dioxaborolan-2-vn-benzaldehyde; A mixture of Pd2(dba)3 (0.0007 mol) and tricyclohexylphosphine (0.0029mol) in dry dioxane (200 ml_) was stirred under N2 for 30 min.and then <strong>[5551-12-2]2-nitro-4-bromobenzaldehyde</strong> (0.040 mol), pinacol diborane (4,4,4',4',5,5,5',5'-octamethyl-2,2'-bi-1,3,2-dioxaborolane) (0.044 mol), and potassium acetate(0.060 mol) were added and the reaction mixture was stirred for 16 hours underN2 at 80C. The mixture was cooled to room temperature and the solvent wasevaporated. The obtained residue was washed with H2O and extracted withCH2CI2. The organic layer was separated, dried (MgSO4), filtered off and thesolvent was evaporated. The residue was purified by short columnchromatography over silica gel (eluent: 100% CH2CI2). The purest productfractions were collected and the solvent was evaporated. The residue wasstirred in hexane, and then the resulting precipitate was filtered off and dried toyield the title compound as a residue.
With potassium acetate; tricyclohexylphosphine;tris-(dibenzylideneacetone)dipalladium(0); In 1,4-dioxane; at 80℃; for 16.5h; A mixture of Pd2(dba)3 (0.0007 mol) and tricyclohexylphosphine (0.0029 mol) in dry dioxane (200 mL) was stirred under N2 for 30 min.and then 2-nitro- 4-bromobenza.dehyde (0.040 mol), pinacol diborane (4,4,4I,4',5,5,5I,5I- octamethyl-2,2'-bi-1 ,3,2-dioxaborolane) (0.044 mol), and potassium acetate (0.060 mol) were added and the reaction mixture was stirred for 16 hours under N2 at 8O0C. The mixture was cooled to room temperature and the solvent was evaporated. The obtained residue was washed with H2O and extracted with CH2CI2. The organic layer was separated, dried (MgSO4), filtered off and the solvent was evaporated. The residue was purified by short column chromatography over silica gel (eluent: 100% CH2CI2). The purest product fractions were collected and the solvent was evaporated. The residue was stirred in hexane, and then the resulting precipitate was filtered off and dried to yield the title compound as a residue.
Historical Records