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[ CAS No. 1184378-11-7 ] {[proInfo.proName]}

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3d Animation Molecule Structure of 1184378-11-7
Chemical Structure| 1184378-11-7
Chemical Structure| 1184378-11-7
Structure of 1184378-11-7 * Storage: {[proInfo.prStorage]}
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Product Details of [ 1184378-11-7 ]

CAS No. :1184378-11-7 MDL No. :MFCD12538969
Formula : C11H8ClN3O2 Boiling Point : -
Linear Structure Formula :- InChI Key :DWXDSXDFBPGMGS-UHFFFAOYSA-N
M.W : 249.65 Pubchem ID :54927341
Synonyms :

Safety of [ 1184378-11-7 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 UN#:
Hazard Statements:H302-H315-H319-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 1184378-11-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1184378-11-7 ]

[ 1184378-11-7 ] Synthesis Path-Downstream   1~1

YieldReaction ConditionsOperation in experiment
With lithium hydroxide monohydrate; water In tetrahydrofuran at 20℃; 69.2 1.2 2-Chloro-5-phenylamino-benzoic acid General procedure: 1.2 2-Chloro-5-phenylamino-benzoic acid A solution of intermediate 1.1 (300 mg) in THF (3.44 mL) was treated with a solution of lithium hydroxide hydrate (144 mg) in H2O (1.15 mL). The reaction mixture was stirred ON at RT, diluted with H2O and extracted twice with EtOAc. The aqueous phase was acidified with a 1M solution of HCl and extracted three times with EtOAc. The organic phases were dried over MgSO4 and concentrated in vacuo to give 266 mg of the titled compound as a light yellow solid.
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