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Chemical Structure| 1191905-07-3 Chemical Structure| 1191905-07-3

Structure of 1191905-07-3

Chemical Structure| 1191905-07-3

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Product Details of [ 1191905-07-3 ]

CAS No. :1191905-07-3
Formula : C17H16N2O3
M.W : 296.32
SMILES Code : O=C(C1=CC2=C(C=C1)C=CN2CC3=CC=C(OC)N=C3)OC

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Application In Synthesis of [ 1191905-07-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1191905-07-3 ]

[ 1191905-07-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 50820-65-0 ]
  • (6-methoxypyridin-3-yl)methyl methanesulfonate [ No CAS ]
  • [ 1191905-07-3 ]
YieldReaction ConditionsOperation in experiment
75% With sodium hydride; In N,N-dimethyl-formamide; at 20℃; for 1h; To a solution of lH-<strong>[50820-65-0]indole-6-carboxylic acid methyl ester</strong> (0.54 g, 3.1 mmol) and (6- methoxypyridin-3-yl)methyl methanesulfonate (0.73 g, 3.4 mmol) in DMF (15 mL) was added NaH (0.9 g, 3.7 mmol). After stirring at room temperature for 1 hr, the solution was diluted with ethyl acetate (100 ml) and washed with water (100 ml). The organic layer was dried (MgSO4), filtered and concentrated. The remaining residue was subjected to flash chromatography (40% ethyl acetate/hexane) to provide 0.68 g (75%) of methyl l-((6-methoxypyridin-3-yl)methyl)-lH-indole-6- carboxylate as a colorless oil.
 

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