Alternatived Products of [ 119430-40-9 ]
Product Details of [ 119430-40-9 ]
CAS No. : | 119430-40-9 |
MDL No. : | MFCD09878317 |
Formula : |
C8H7Br2NO
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
292.96
|
Pubchem ID : | - |
Synonyms : |
|
Safety of [ 119430-40-9 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 119430-40-9 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Upstream synthesis route of [ 119430-40-9 ]
- Downstream synthetic route of [ 119430-40-9 ]
- 1
-
[ 626-40-4 ]
-
[ 108-24-7 ]
-
[ 119430-40-9 ]
Yield | Reaction Conditions | Operation in experiment |
96% |
With potassium carbonate In dichloromethane at 20℃; |
1.1 M 1-I-1 Synthesis
The starting material, 3,5-dibromoaniline(125.35 g, 499.6 mmol) to a round bottom flask in CH2Cl2 (2498ml) todissolve after, acetic anhydride (56.10 g, 549.5 mmol) and K2CO3 (82.85 g,599.5 mmol) at room temperature and the mixture It was stirred. Aftercompletion of reaction, then extracted with water and CH2Cl2 and the organiclayer the product was dried with MgSO4 and concentrated to 140.50 g wasobtained (96% yield). |
Reference:
[1]Current Patent Assignee: DUK SAN NEOLUX CO., LTD. - KR101535606, 2015, B1
Location in patent: Paragraph 0203-0206
[2]Holleman
[Recueil des Travaux Chimiques des Pays-Bas, 1906, vol. 25, p. 202][Recueil des Travaux Chimiques des Pays-Bas, 1908, vol. 27, p. 151,159]
Chattaway; Orton
[Chemische Berichte, 1900, vol. 33, p. 2399]
- 2
-
[ 119430-40-9 ]
-
[ 168618-42-6 ]
-
C15H14BrNOS
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
73% |
With tetrakis(triphenylphosphine) palladium(0); sodium hydroxide In tetrahydrofuran; water at 80℃; |
1.2 (2) M 1-II-1 Synthesis
Wherein M 1-I-1 (293.97 g, 1003.5 mmol) to around bottom flask was charged with THF (3000ml) to dissolve later, (2 -(methylthio) phenyl) boronic acid (140.50 g, 836.2 mmol), Pd (PPh3) 4 (48.31 g,41.8 mmol), NaOH (100.35 g, 2508.6 mmol), water (1500ml) was added and themixture was stirred at 80 . It was obtained:When the reaction is complete, the organic layer was dried and extracted withwater and CH2Cl2 over MgSO4 and concentrated to silicagel column and theproduct was recrystallized 205.26 g (73% yield) and the resulting compound then. |