Home Cart Sign in  
Chemical Structure| 1195781-15-7 Chemical Structure| 1195781-15-7

Structure of 1195781-15-7

Chemical Structure| 1195781-15-7

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1195781-15-7 ]

CAS No. :1195781-15-7
Formula : C14H12FNO3
M.W : 261.25
SMILES Code : OC1=CC=C(C=C1F)NC(OCC2=CC=CC=C2)=O
MDL No. :MFCD29044724

Safety of [ 1195781-15-7 ]

Application In Synthesis of [ 1195781-15-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1195781-15-7 ]

[ 1195781-15-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 52092-47-4 ]
  • [ 1195781-15-7 ]
  • [ 1195781-16-8 ]
YieldReaction ConditionsOperation in experiment
83% With caesium carbonate; In dimethyl sulfoxide; at 20℃; for 3h; To a solution of benzyl (3-fluoro-4- hydroxyphenyl) carbamate (80 g, 252 mmol) in dimethyl sulfoxide (600 mL) were added cesium carbonate (123 g, 378 mmol) and 5- chloro-2-nitropyridine (40 g, 252 mmol), and the mixture was <n="138"/>stirred at room temperature for 3 hr. Saturated aqueous sodium hydrogen carbonate (1000 mL) and water (1000 mL) were added to the reaction mixture, and the mixture was extracted twice with ethyl acetate. The combined organic layer was washed with saturated brine, dried over anhydrous magnesium sulfate and filtered. The solvent was evaporated under reduced pressure, and the residue was washed with hexane/ethyl acetate (=3/1) and collected by filtration to give the title compound (79.8 g, 83percent) . 1H-NMR (CDCl3, 300MHz) delta 5.23 (2H, S), 6.82 (IH, s) , 7.05 -7.19 (2H, m) , 7.31 - 7.44 (6H, m) , 7.59 (IH, dd, J = 12.3, 2.4 Hz), 8.24 (IH, d, J = 9.0 Hz), 8.32 (IH, d, J = 2.7 Hz) .
 

Historical Records