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Chemical Structure| 1198085-23-2 Chemical Structure| 1198085-23-2

Structure of 1198085-23-2

Chemical Structure| 1198085-23-2

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Product Details of [ 1198085-23-2 ]

CAS No. :1198085-23-2
Formula : C28H22Cl2F3N3O4
M.W : 592.39
SMILES Code : O=C(O)C1=CC=C(CN(C2=CC=C(OCC3=C(C4CC4)ON=C3C5=C(Cl)C=CC=C5Cl)N=C2C(F)(F)F)C)C=C1

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Application In Synthesis of [ 1198085-23-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1198085-23-2 ]

[ 1198085-23-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 154350-29-5 ]
  • [ 1198085-23-2 ]
  • C31H27Cl2F3N4O5S [ No CAS ]
YieldReaction ConditionsOperation in experiment
71% With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20℃; for 16h; A solution of compound 2 (12 mg, 0.02 mmol), <strong>[154350-29-5]cyclopropanesulfonamide</strong> (4.9 mg, 0.041 mmol), EDC (7.8 mg, 0.04 mmol), and DMAP (5.0 mg, 0.04 mmol) in DCM (1.0 mL) was stirred at rt for 16 h, then quenched with brine, and extracted with EtOAc. The combined organic layers were washed with brine and concentrated. The residue was purified by chromatography on silica gel using hexane/acetone (100/0 to 50/50, 10 min) to give desired product 1 as a white solid (10 mg, 71%), LC-MS, ES": 693.09 (M-l).
 

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