Home Cart 0 Sign in  

[ CAS No. 1206-15-1 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 1206-15-1
Chemical Structure| 1206-15-1
Structure of 1206-15-1 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Quality Control of [ 1206-15-1 ]

Related Doc. of [ 1206-15-1 ]

Alternatived Products of [ 1206-15-1 ]
Product Citations

Product Details of [ 1206-15-1 ]

CAS No. :1206-15-1 MDL No. :MFCD00065276
Formula : C13H15NO Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 201.26 Pubchem ID :-
Synonyms :

Safety of [ 1206-15-1 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501 UN#:N/A
Hazard Statements:H302-H312-H332 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1206-15-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1206-15-1 ]

[ 1206-15-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 110-52-1 ]
  • [ 104-47-2 ]
  • [ 1206-15-1 ]
YieldReaction ConditionsOperation in experiment
75% With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 2h; 1.1 Step 1: Preparation of1 -(4-methoxyphenyl)cyclopentane-1 -carbonitrile Sodium hydride (2.85 g, 71.34 mmol) was dissolved in dimethylformamide (50 ml), to which 2-(4- methoxyphenyl)acetonitrile (5.0 g, 33.97 mmol) and 1,4- dibromobutane (8.80 g, 40.77 mmol) were loaded at 00 C. The reaction mixture was stirred at room temperature for 2 hours. Water was added thereto to terminate the reaction, followed by extraction twice with ethylacetate. The extracted organic layer was dried over sodium sulfate and then filtered. The solvent was eliminated by distillation under reduced pressure. Then, purification was performed by silica gel colunm chromatography (eluent: ethylacetate/ hexane, 1/1) to give the target compound 1-(4-methoxyphe- nyl)cyclopentane-1-carbonitrile as a white solid (5.10 g, 25.3 mmol, yield: 75%).‘H-NMR (300 MHz, CDC13) ö 7.36 (d, J=8.7 Hz, 2H), 7.36 (d, J=9.0 Hz, 2H), 3.81 (s, 3H), 2.44-2.46 (m, 2H),1.91-2.04 (m, 6H); LC/MS 202.1[M+H].
70.7% With sodium hydroxide at 110 - 120℃; for 12h;
70% With sodium hydride In diethyl ether; dimethyl sulfoxide
Recommend Products
Same Skeleton Products
Historical Records