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Chemical Structure| 1210048-04-6 Chemical Structure| 1210048-04-6

Structure of 1210048-04-6

Chemical Structure| 1210048-04-6

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Product Details of [ 1210048-04-6 ]

CAS No. :1210048-04-6
Formula : C16H20BNO3
M.W : 285.15
SMILES Code : CC1(C)C(C)(C)OB(C2=CC=C3N=CC=C(OC)C3=C2)O1

Safety of [ 1210048-04-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 1210048-04-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1210048-04-6 ]

[ 1210048-04-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 874792-20-8 ]
  • [ 73183-34-3 ]
  • [ 1210048-04-6 ]
YieldReaction ConditionsOperation in experiment
With potassium acetate;dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; In 1,4-dioxane; at 110℃;Inert atmosphere; Under an argon atmosphere, 150 mg of example 87A was dissolved in 4 ml dioxane. Then 111.3 mg (1.134 mmol) potassium acetate, 41.2 mg (0.050 mmol) of 1, l'-bis-(diphenylphosphino)- ferrocene palladium(II) chloride-dichloromethane complex and 176 mg (0.693 mmol) of 4,4,4'4'5,5,5'5'-octamethyl-2,2'-bi-l,3,2-dioxaborolan were added. The reaction mixture was stirred overnight at 1100C oil bath temperature. After cooling, dichloromethane was added to the reaction mixture and it was filtered on kieselguhr. It was washed again with ethyl acetate. The filtrate was concentrated in a rotary evaporator at reduced pressure and dried under high vacuum. We obtained 227 mg of 4-methoxy-6-(4,4,5,5-tetramethyl-l,3,2-dioxaborolan-2-yl)quinoline [47%, (LC-MS)] as raw product. This was reacted subsequently without further purification.
 

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