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Chemical Structure| 1214242-09-7 Chemical Structure| 1214242-09-7

Structure of 1214242-09-7

Chemical Structure| 1214242-09-7

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Product Details of [ 1214242-09-7 ]

CAS No. :1214242-09-7
Formula : C12H19BN2O2
M.W : 234.10
SMILES Code : NC1=NC(C)=CC(B2OC(C)(C)C(C)(C)O2)=C1
MDL No. :MFCD18382799

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Application In Synthesis of [ 1214242-09-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1214242-09-7 ]

[ 1214242-09-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 36340-61-1 ]
  • [ 73183-34-3 ]
  • [ 1214242-09-7 ]
YieldReaction ConditionsOperation in experiment
With potassium acetate;tris-(dibenzylideneacetone)dipalladium(0); tricyclohexylphosphine; In 1,4-dioxane; at 120℃; for 0.5h;Microwave irradiation; A solution <strong>[36340-61-1]4-chloro-6-methylpyridin-2-amine</strong> (1.0 equiv.), potassium acetate (3.0 equiv.), bis(pinacolato)diboron (2.0 equiv.), tricyclohexylphosphine (0.075 equiv.) and Pd2(dba)3 (0.05 equiv.) in dioxane (0.12 M) was heated at 120 C. in a microwave for 2*15 minutes. The solution was filtered through a 1 muM HPLC filter, concentrated. DME was added and the resulting solid was filtered and rinsed with CH2Cl2. The combined filtrate was concentrated and pumped to yield 6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine which was used directly. LC/MS=153.0 (M+H of corresponding HetB(OH)2), LC=0.35 min.
 

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