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Chemical Structure| 1218935-58-0 Chemical Structure| 1218935-58-0

Structure of 1218935-58-0

Chemical Structure| 1218935-58-0

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Product Details of [ 1218935-58-0 ]

CAS No. :1218935-58-0
Formula : C15H19F2NO2
M.W : 283.31
SMILES Code : CC(C)(OC(N1CCC[C@@H]1C2=C(C=CC(F)=C2)F)=O)C
MDL No. :MFCD28009005

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Application In Synthesis of [ 1218935-58-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1218935-58-0 ]

[ 1218935-58-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1218935-58-0 ]
  • [ 1218935-59-1 ]
YieldReaction ConditionsOperation in experiment
98% With hydrogenchloride; In tetrahydrofuran; water; for 2h; 20 mmol of the intermediate A-3 was dissolved in tetrahydrofuran 50 mL, Add 100mmol35% hydrochloric acid solution stirring, after 2 hours of reaction, the reaction solution was alkalized to basic with 2M NaOH. Extracted twice with ethyl acetate, After recovering ethyl acetate, 3.6 g of product was obtained, and the yield was 98%.HPLC purity ? 96%, HPLC chiral purity ? 99%.
 

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