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Chemical Structure| 122097-66-9 Chemical Structure| 122097-66-9

Structure of 122097-66-9

Chemical Structure| 122097-66-9

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Product Details of [ 122097-66-9 ]

CAS No. :122097-66-9
Formula : C11H9ClN2O
M.W : 220.66
SMILES Code : O=C(NC1=CC=C2N=CC=CC2=C1)CCl
MDL No. :MFCD06800443

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Application In Synthesis of [ 122097-66-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 122097-66-9 ]

[ 122097-66-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 580-15-4 ]
  • [ 79-04-9 ]
  • [ 122097-66-9 ]
YieldReaction ConditionsOperation in experiment
75% General procedure: To a solution of substituted aniline (compounds 1a-1t) or 5-aminoindole and <strong>[580-15-4]6-aminoquinoline</strong> (1.0 equiv.) in dichloromethane (CH2Cl2) (15mL) at 0C, potassium carbonate (K2CO3) (2.0 equiv.) was added. The reaction was stirred at 0C for 15min. Into this stirring solution, chloroacetyl chloride (1.0 equiv.) was added dropwise at 0C. The mixture was stirred for 2hat room temperature. After completion of the reaction, water (20mL) was added, and the mixture was extracted with dichloromethane. The organic solvent phase was concentrated under vacuum to afford the desired compounds 2a-2t, 5a and 5b.
 

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