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Chemical Structure| 1232407-19-0 Chemical Structure| 1232407-19-0

Structure of 1232407-19-0

Chemical Structure| 1232407-19-0

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Product Details of [ 1232407-19-0 ]

CAS No. :1232407-19-0
Formula : C9H9BrO2
M.W : 229.07
SMILES Code : CC(C1=CC=CC(OC)=C1Br)=O
MDL No. :MFCD09265217

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Application In Synthesis of [ 1232407-19-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1232407-19-0 ]

[ 1232407-19-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 88377-29-1 ]
  • [ 1232407-19-0 ]
  • 2
  • [ 1036378-83-2 ]
  • [ 1232407-19-0 ]
  • C27H22O2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
49.1 g With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; In 1,4-dioxane; water; at 60℃; for 15h;Reflux; 30.8 g (134.47 mmol) of 1-(2-bromo-3-methoxyphenyl)ethanone and 52.7 g (147.92 mmol) of the compound [65-1] were placed in a 2 L reaction flask, Add 530 ml and raise the temperature. 4.66 g (4.034 mmol) of tetrakis (triphenylphosphine) palladium (0) was added at 60 C. 27.88 g (201.71 mmol) of potassium carbonate dissolved in distilled water was added and the mixture was refluxed and stirred for 15 hours. When the reaction is completed, the reaction mixture is cooled to room temperature, extracted with ethyl acetate / distilled water, and treated with anhydrous magnesium sulfate. The reaction mixture is distilled under reduced pressure. Separation and purification were conducted by silica gel chromatography to obtain 49.1 g (96.5 wt%) of intermediate compound [65-2] in a clear oil state
 

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