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Chemical Structure| 1248826-59-6 Chemical Structure| 1248826-59-6

Structure of 1248826-59-6

Chemical Structure| 1248826-59-6

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Product Details of [ 1248826-59-6 ]

CAS No. :1248826-59-6
Formula : C14H19NO3
M.W : 249.31
SMILES Code : O=C1N(CC2=CC=C(OC)C=C2)CC(C)(C)C1O
MDL No. :MFCD30002296

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Application In Synthesis of [ 1248826-59-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1248826-59-6 ]

[ 1248826-59-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 327056-62-2 ]
  • [ 1248826-59-6 ]
  • 5-[1-(4-methoxybenzyl)-4,4-dimethyl-2-oxopyrrolidin-3-yloxy]pyridine-2-carbonitrile [ No CAS ]
YieldReaction ConditionsOperation in experiment
With caesium carbonate; In acetonitrile; at 60℃; To a solution of 3-hydroxy-1-(4-methoxy-benzyl)-4,4-dimethyl-pyrrolidin-2-one (50 mg) and 5-fluoropyridine-2-carbonitrile (29.3 mg) in MeCN (5 mL) was added Cs2CO3 (0.2 g) at RT. The mixture was stirred overnight at 60 C. The mixture was filtered. The filtrate was concentrated under vacuum. The residue was purified by preparative TLC to provide 5-[1-(4-methoxy-benzyl)-4,4-dimethyl-2-oxo-pyrrolidin-3-yloxy]-pyridine-2-carbonitrile. MS ESI+: m/z=352 [M+H]+.
 

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