[ CAS No. 1272412-72-2 ]

Name: 1272412-72-2|tert-Butyl 1,6-diazaspiro[3.3]heptane-6-carboxylate|98%
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Quality Control of [ 1272412-72-2 ]

COA NMR CNMR HPLC LC-MS

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SDS Specification

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Product Details of [ 1272412-72-2 ]

CAS No. :	1272412-72-2	MDL No. :	MFCD18782894
Formula :	C₁₀H₁₈N₂O₂	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	WDVOLHDNUMLNAK-UHFFFAOYSA-N
M.W :	198.26 g/mol	Pubchem ID :	56828077
Synonyms :

Safety of [ 1272412-72-2 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P261-P305+P351+P338	UN#:	N/A
Hazard Statements:	H315-H319-H335	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 1272412-72-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 1272412-72-2 ]

[ 1272412-72-2 ] Synthesis Path-Downstream 1~21

1
(S)-N-(4-chloro-2-(2-(5-chloro-6-methylpyrazolo[1,5-a]-pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide [ No CAS ]
[ 1272412-72-2 ]
(S)-tert-butyl 1-(2-(1-(5-chloro-2-(methylsulfonamido)benzoyl)piperidin-2-yl)-6-methylpyrazolo[1,5-a]pyrimidin-5-yl)-1,6-diazaspiro[3.3]heptane-6-carboxylate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
35%	With triethylamine In methanol at 75℃;	157 Example 157 Preparation of Compound 42 [1014] Triethylamine (0.100 mL, 0.717 mmol) was added to a mixture of intermediate 11 (71 mg, 0.147 mmol) and tert-butyl 1,6-diazaspiro[3.3]heptane-6-carboxylate (114 mg, 0.575 mmol) in 5 mL of methanol at room temperature. After heating at 75° C. overnight, reaction mixture was cooled to room temperature and concentrated under reduced pressure. The remaining residue was purified by silica gel column chromatography (5-75% ethyl acetate in hexanes) to yield (S)-tert-butyl 1-(2-(1-(5-chloro-2-(methylsulfonamido)benzoyl)piperidin-2-yl)-6-methylpyrazolo[1,5-a]pyrimidin-5-yl)-1,6-diazaspiro[3.3]heptane-6-carboxylate as a solid (33 mg, 35%). This solid was dissolved in 3 mL of dichloromethane and trifluoroacetic acid (0.15 mL, 1.95 mmol) was added. After stirring overnight and reaction mixture was concentrated under reduced pressure to yield compound 42 (33 mg, 99%) as a white solid. [1016] LCMS m/z [M+H]+ C25H30ClN7O3 requires: 544.18. Found 544.37. [1017] HPLC Tr (min), purity %: 5.67, 96%.

Reference： [1]Current Patent Assignee: GILEAD SCIENCES INC - US2013/273037, 2013, A1 Location in patent: Paragraph 1014-1017

2
[ 1272412-72-2 ]
1-(2-methoxyphenyl)-6-(3-((4-methyl-5-phenyl-4H-1,2,4-triazol-3-yl)thio)propyl)-1,6-diazaspiro[3.3]heptane [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 3 steps 1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; ruphos; sodium t-butanolate / 1,4-dioxane / 0.33 h / 100 °C 2: trifluoroacetic acid / dichloromethane / 3 h / 20 °C 3: caesium carbonate / acetonitrile / 12 h / 70 °C

Reference： [1]Reilly, Sean W.; Griffin, Suzy; Taylor, Michelle; Sahlholm, Kristoffer; Weng, Chi-Chang; Xu, Kuiying; Jacome, Daniel A.; Luedtke, Robert R.; Mach, Robert H. [Journal of Medicinal Chemistry, 2017, vol. 60, # 23, p. 9905 - 9910]

3
[ 1272412-72-2 ]
C₁₂H₁₆N₂O [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; ruphos; sodium t-butanolate / 1,4-dioxane / 0.33 h / 100 °C 2: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

4
[ 1272412-72-2 ]
C₁₁H₁₃FN₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; ruphos; sodium t-butanolate / 1,4-dioxane / 0.33 h / 100 °C 2: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

5
[ 1272412-72-2 ]
1-(4-fluorophenyl)-6-(3-((4-methyl-5-phenyl-4H-1,2,4-triazol-3-yl)thio)propyl)-1,6-diazaspiro[3.3]heptane [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 3 steps 1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; ruphos; sodium t-butanolate / 1,4-dioxane / 0.33 h / 100 °C 2: trifluoroacetic acid / dichloromethane / 3 h / 20 °C 3: caesium carbonate / acetonitrile / 12 h / 70 °C

6
[ 1272412-72-2 ]
C₁₇H₂₄N₂O₃ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium t-butanolate; ruphos In 1,4-dioxane at 100℃; for 0.333333h;

7
[ 1272412-72-2 ]
C₁₆H₂₁FN₂O₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium t-butanolate; ruphos In 1,4-dioxane at 100℃; for 0.333333h;

8
[ 763114-26-7 ]
[ 1272412-72-2 ]
tert-butyl 1-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)-methyl)benzoyl)-1,6-diazaspiro[3.3]heptane-6-carboxylate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
98%	With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In tetrahydrofuran at 60℃; for 12h;

Reference： [1]Reilly, Sean W.; Puentes, Laura N.; Wilson, Khadija; Hsieh, Chia-Ju; Weng, Chi-Chang; Makvandi, Mehran; Mach, Robert H. [Journal of Medicinal Chemistry, 2018, vol. 61, # 12, p. 5367 - 5379]

9
[ 1272412-72-2 ]
4-(4-fluoro-3-(1,6-diazaspiro[3.3]heptane-1-carbonyl)benzyl)-phthalazin-1(2H)-one [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / tetrahydrofuran / 12 h / 60 °C 2: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

10
[ 1272412-72-2 ]
4-(3-(6-(cyclopropanecarbonyl)-1,6-diazaspiro[3.3]heptane-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 3 steps 1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / tetrahydrofuran / 12 h / 60 °C 2: trifluoroacetic acid / dichloromethane / 3 h / 20 °C 3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / tetrahydrofuran / 12 h / 60 °C

11
[ 1272412-72-2 ]
[ 407-25-0 ]
tert-butyl 1-(2,2,2-trifluoroacetyl)-1,6-diazaspiro[3.3]heptane-6-carboxylate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
81%	With triethylamine In dichloromethane at 0 - 25℃; for 18h;

Reference： [1]Bosset, Cyril; Beucher, Hélène; Bretel, Guillaume; Pasquier, Elisabeth; Queguiner, Laurence; Henry, Cyril; Vos, Ann; Edwards, James P.; Meerpoel, Lieven; Berthelot, Didier [Organic Letters, 2018, vol. 20, # 19, p. 6003 - 6006]

12
[ 1272412-72-2 ]
tert-butyl 5-(2-methylquinolin-4-yl)-1-(2,2,2-trifluoroacetyl)-1,6-diazaspiro[3.3]heptane-6-carboxylate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: triethylamine / dichloromethane / 18 h / 0 - 25 °C 2: [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; trifluoroacetic acid; sodium persulfate / acetonitrile; water / 30 h / 20 - 25 °C / Sealed tube; Inert atmosphere; Irradiation

13
[ 1272412-72-2 ]
[ 5783-36-8 ]
C₂₄H₂₈N₂O₄ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 18h;	Step a). Tert-butyl 3-(3'-methoxy-[1,1'-biphenyl]-4-carboxamido)azetidine-1-carboxylate45. General procedure: To a stirred solution of 3'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (228 mg, 1 mmol),and tert-butyl 3-amino-3-methylazetidine-1-carboxylate (189.2 mg, 1.02 mmol.) and N,Ndiisopropyl-ethylamine (452.4 mg, 3.5 mmol) in DMF (5 mL) was added HBTU (1.32g, 3.48mmol). The resulting mixture was stirred at room temperature for 18 hours. The reactionmixture was partitioned between water (30 mL) and ethyl acetate (30 mL) and the aqueouslayer was extracted with ethyl acetate (50 mL). The combined organic extracts were washedwith saturated NaHCO3 (30 mL), and brine (30 mL). The organic layer was dried overNa2SO4 and concentrated under reduced pressure. The residue was purified on silica gel(Biotage; eluting solvents hexane: EtOAc 4/1 ratio) to afford tert-butyl 3-(3'-methoxy-[1,1'-biphenyl]-4-carboxamido)-3-methylazetidine-1-carboxylate as a colorless solid in 80% yield.

Reference： [1]Malamas, Michael S.; Farah, Shrouq I.; Lamani, Manjunath; Pelekoudas, Dimitrios N.; Perry, Nicholas Thomas; Rajarshi, Girija; Miyabe, Christina Yume; Chandrashekhar, Honrao; West, Jay; Pavlopoulos, Spiro; Makriyannis, Alexandros [Bioorganic and Medicinal Chemistry, 2020, vol. 28, # 1]

14
[ 1272412-72-2 ]
C₁₉H₂₀N₂O₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 18 h / 20 °C 2: trifluoroacetic acid / dichloromethane / 6 h / 20 °C

15
[ 1272412-72-2 ]
C₁₈H₂₀N₂O₃S [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 18 h / 20 °C 2: trifluoroacetic acid / dichloromethane / 6 h / 20 °C

16
[ 1272412-72-2 ]
1-(3'-methoxy-[1,1'-biphenyl]-4-carbonyl)-1,6-diazaspiro[3.3]heptane-6-carbonitrile [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 3 steps 1.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 18 h / 20 °C 2.1: trifluoroacetic acid / dichloromethane / 6 h / 20 °C 3.1: triethylamine / dichloromethane 3.2: 20 °C

17
[ 1272412-72-2 ]
1-((3'-methoxy-[1,1'-biphenyl]-4-yl)sulfonyl)-1,6-diazaspiro[3.3]heptane-6-carbonitrile [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 3 steps 1.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 18 h / 20 °C 2.1: trifluoroacetic acid / dichloromethane / 6 h / 20 °C 3.1: triethylamine / dichloromethane 3.2: 20 °C

18
[ 1272412-72-2 ]
3'-methoxy-[1,1'-biphenyl]-4-sulfonyl chloride [ No CAS ]
C₂₃H₂₈N₂O₅S [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 18h;	Step a). Tert-butyl 3-(3'-methoxy-[1,1'-biphenyl]-4-carboxamido)azetidine-1-carboxylate 45. General procedure: To a stirred solution of 3'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (228 mg, 1 mmol),and tert-butyl 3-amino-3-methylazetidine-1-carboxylate (189.2 mg, 1.02 mmol.) and N,Ndiisopropyl-ethylamine (452.4 mg, 3.5 mmol) in DMF (5 mL) was added HBTU (1.32g, 3.48mmol). The resulting mixture was stirred at room temperature for 18 hours. The reactionmixture was partitioned between water (30 mL) and ethyl acetate (30 mL) and the aqueouslayer was extracted with ethyl acetate (50 mL). The combined organic extracts were washedwith saturated NaHCO3 (30 mL), and brine (30 mL). The organic layer was dried overNa2SO4 and concentrated under reduced pressure. The residue was purified on silica gel(Biotage; eluting solvents hexane: EtOAc 4/1 ratio) to afford tert-butyl 3-(3'-methoxy-[1,1'-biphenyl]-4-carboxamido)-3-methylazetidine-1-carboxylate as a colorless solid in 80% yield.

19
[ 1272412-72-2 ]
C₆H₁₂N₂*2C₂HF₃O₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: sodium tris(acetoxy)borohydride / lithium hydroxide monohydrate / 16 h / 20 °C / Inert atmosphere 2: 1 h / 0 °C
	Multi-step reaction with 2 steps 1: sodium tris(acetoxy)borohydride; methanol / lithium hydroxide monohydrate / 16 h / 20 °C / Inert atmosphere 2: dichloromethane / 1 h / 0 °C

Reference： [1]Current Patent Assignee: BIOARDIS LLC - WO2022/87624, 2022, A1
[2]Current Patent Assignee: BIOARDIS LLC - WO2022/87624, 2022, A1

20
[ 67-56-1 ]
[ 50-00-0 ]
[ 1272412-72-2 ]
tert-butyl 1-methyl-1,6-diazaspiro[3.3]heptane-6-carboxylate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
56%	With sodium tris(acetoxy)borohydride In lithium hydroxide monohydrate at 20℃; for 16h; Inert atmosphere;	Step A. A mixture of tert-butyl 1,6-diazaspiro[3.3]heptane-6-carboxylate (0.5 g, 2.52 mmol), formaldehyde aqueous solution (37%) (2 g, 25.25 mmol) and sodium triacetoxyborohydride (1.6 g, 7.56 mmol) in MeOH (20 mL) was stirred for 16 h at rt under N2. The mixture was diluted with DCM (50 mL), the organic layer was washed with water and sodium bicarbonate solution, dried over Na2SO4, filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by chromatography on silica gel (eluting with PE/EA = 2:1) to give tert- butyl 1-methyl-1,6-diazaspiro[3.3]heptane-6-carboxylate (300 mg, 56 % yield) as an oil. Mass Spectrum (ESI) m/z = 213 (M+1).
56%	With sodium tris(acetoxy)borohydride In lithium hydroxide monohydrate at 20℃; for 16h; Inert atmosphere;	Step A. A mixture of tert-butyl 1,6-diazaspiro[3.3]heptane-6-carboxylate (0.5 g, 2.52 mmol), formaldehyde aqueous solution (37%) (2 g, 25.25 mmol) and sodium triacetoxyborohydride (1.6 g, 7.56 mmol) in MeOH (20 mL) was stirred for 16 h at rt under N2. The mixture was diluted with DCM (50 mL), the organic layer was washed with water and sodium bicarbonate solution, dried over Na2SO4, filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by chromatography on silica gel (eluting with PE/EA = 2:1) to give tert- butyl 1-methyl-1,6-diazaspiro[3.3]heptane-6-carboxylate (300 mg, 56 % yield) as an oil. Mass Spectrum (ESI) m/z = 213 (M+1).

Reference： [1]Current Patent Assignee: BIOARDIS LLC - WO2022/87624, 2022, A1 Location in patent: Paragraph 0305
[2]Current Patent Assignee: BIOARDIS LLC - WO2022/87624, 2022, A1 Location in patent: Paragraph 0305

21
[ 50-00-0 ]
[ 1272412-72-2 ]
tert-butyl 1-methyl-1,6-diazaspiro[3.3]heptane-6-carboxylate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
56%	With methanol; sodium tris(acetoxy)borohydride In lithium hydroxide monohydrate at 20℃; for 16h; Inert atmosphere;	Step A. A mixture of tert-butyl 1,6-diazaspiro[3.3]heptane-6-carboxylate (0.5 g, 2.52 mmol), formaldehyde aqueous solution (37%) (2 g, 25.25 mmol) and sodium triacetoxyborohydride (1.6 g, 7.56 mmol) in MeOH (20 mL) was stirred for 16 h at rt under N2. The mixture was diluted with DCM (50 mL), the organic layer was washed with water and sodium bicarbonate solution, dried over Na2SO4, filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by chromatography on silica gel (eluting with PE/EA = 2:1) to give tert- butyl 1-methyl-1,6-diazaspiro[3.3]heptane-6-carboxylate (300 mg, 56 % yield) as an oil. Mass Spectrum (ESI) m/z = 213 (M+1).

Reference： [1]Current Patent Assignee: BIOARDIS LLC - WO2022/87624, 2022, A1 Location in patent: Paragraph 0305

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P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
{[ item.p_purity ]}	{[ item.pr_size ]}	{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]}	{[ getRatePrice(item.pr_usd, 1,1) ]}	{[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]}	{[ item.pr_usastock ]}	Inquiry -	{[ item.pr_chinastock ]}	Inquiry -

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 1272412-72-2 ]

Quality Control of [ 1272412-72-2 ]

Related Doc. of [ 1272412-72-2 ]

Product Details of [ 1272412-72-2 ]

Safety of [ 1272412-72-2 ]

Application In Synthesis of [ 1272412-72-2 ]

[ 1272412-72-2 ] Synthesis Path-Downstream 1~21

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry