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Chemical Structure| 127423-65-8 Chemical Structure| 127423-65-8

Structure of 127423-65-8

Chemical Structure| 127423-65-8

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Product Details of [ 127423-65-8 ]

CAS No. :127423-65-8
Formula : C7H15NO3S
M.W : 193.26
SMILES Code : CS(=O)(OC1CCN(C)CC1)=O

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Application In Synthesis of [ 127423-65-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 127423-65-8 ]

[ 127423-65-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 127423-65-8 ]
  • [ 35344-95-7 ]
  • 1-(1-methyl-4-piperidyl)pyrazole-4-carbaldehyde [ No CAS ]
YieldReaction ConditionsOperation in experiment
190 mg With caesium carbonate; In N,N-dimethyl-formamide; at 0 - 80℃; for 16h; To a stirred solution of lH-<strong>[35344-95-7]pyrazole-4-carbaldehyde</strong> 12-4 (300 mg, 3. 12 mmol) in DMF (5 mL) was added (1- methyl-4-piperidyl) methanesulfonate 12-3 (724.08 mg, 3.75 mmol) and cesium carbonate (2.54 g, 7.81 mmol) at 0C. The reaction mixture was then heated at 80C for 16 hours and then diluted with ice cold water, extracted with ethyl acetate, washed with brine, dried over sodium sulfate, and concentrated under reduced pressure. The crude was purified by flash chromatography using 0%- 10% MeOH-DCM to afford (l-methyl-4-piperidyl)<strong>[35344-95-7]pyrazole-4-carbaldehyde</strong> 12-5 (190 mg, 983.21 umol, 31.49% yield) as a brown liquid. LCMS: ES+ 194.1.
 

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