Alternatived Products of [ 1274804-51-1 ]
Product Details of [ 1274804-51-1 ]
CAS No. : | 1274804-51-1 |
MDL No. : | MFCD22573930 |
Formula : |
C11H18N4O2
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
238.29
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 1274804-51-1 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 1274804-51-1 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 1274804-51-1 ]
- 1
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[ 624-84-0 ]
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[ 190900-21-1 ]
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[ 1274804-51-1 ]
Yield | Reaction Conditions | Operation in experiment |
61% |
|
STEP A: To a stirred solution of ter/-butyl 5-oxo-l,4-diazepane-l-carboxylate (1000 mg, 4.67 mmol) in dichloromethane (10 mL) was added trimethyloxonium tetrafluoroborate (690 mg, 4.67 mmol) under nitrogen and the reaction mixture was stirred for 16 hours. At this point, formic hydrazine (280 mg, 4.67 mmol) indichloromethane (8 mL) was added, and the reaction was stirred for an additional 16 hours. The reaction mixture was then concentrated under reduced pressure, resuspended in methanol (10 mL), and heated to reflux for 16 hours. The reaction mixture was concentrated and purified via flash chromatography on silica gel (0-50percent 2N NH3 in methanol in CH2C12) to afford 4,5,7,8-tetrahydro-l,2,3a,6-tetraaza-azulene-6-carboxylic acid tert-butyl ester (680 mg, 61percent yield). MS [m/z; (M+l)+]: 319.3 |
- 2
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[ 471-31-8 ]
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[ 190900-21-1 ]
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[ 1274804-51-1 ]