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Chemical Structure| 1289472-57-6 Chemical Structure| 1289472-57-6

Structure of 1289472-57-6

Chemical Structure| 1289472-57-6

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Product Details of [ 1289472-57-6 ]

CAS No. :1289472-57-6
Formula : C21H16BrN
M.W : 362.26
SMILES Code : CC1(C)C2=C(C=CC=C2)N3C4=C(C5=C3C=CC=C5)C=C(Br)C=C14

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Application In Synthesis of [ 1289472-57-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1289472-57-6 ]

[ 1289472-57-6 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 952514-79-3 ]
  • [ 1289472-57-6 ]
  • [ 1289472-71-4 ]
YieldReaction ConditionsOperation in experiment
With potassium phosphate monohydrate; tris-(o-tolyl)phosphine; In 1,4-dioxane; water; toluene; for 5h;Reflux; Example 7 [6-(1-Phenyl-1H-benzimidazol-2-yl)phenyl]-8,8-dimethyl-8H-indolo[3,2,1-de]acridine 0.27 g (0.9 mmol) of tri-o-tolylphosphine and then 33.5 mg (0.15 mmol) of palladium(II) acetate are added with vigorous stirring to a degassed suspension of 10.1 g (28 mmol) of 6-bromo-8,8-dimethyl-8H-indolo[3,2,1-de]-acridine and 9.42 g (30 mmol) of benzimidazoleboronic acid and 7.8 g (31.5 mmol) of potassium phosphate hydrate in a mixture of 7.5 ml of dioxane, 15 ml of toluene and 18 ml of water. After heating under reflux for 5 h, the mixture is allowed to cool. The precipitate is filtered off with suction, washed three times with 10 ml of ethanol/water (1:1, v:v) and three times with 5 ml of ethanol, subsequently dried in vacuo and recrystallised from dioxane. Yield: 12.46 g (22.5 mmol), 81% of theory, purity according to 1H-NMR about 99.9%.
  • 2
  • [ 902518-11-0 ]
  • [ 1289472-57-6 ]
 

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