Home Cart 0 Sign in  
X

[ CAS No. 1290634-35-3 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
3d Animation Molecule Structure of 1290634-35-3
Chemical Structure| 1290634-35-3
Chemical Structure| 1290634-35-3
Structure of 1290634-35-3 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 1290634-35-3 ]

Related Doc. of [ 1290634-35-3 ]

Alternatived Products of [ 1290634-35-3 ]
Product Citations

Product Details of [ 1290634-35-3 ]

CAS No. :1290634-35-3 MDL No. :MFCD22380537
Formula : C10H8BrNO Boiling Point : -
Linear Structure Formula :- InChI Key :ZZSFZIKRCCTBSV-UHFFFAOYSA-N
M.W : 238.08 Pubchem ID :20800104
Synonyms :

Safety of [ 1290634-35-3 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501 UN#:
Hazard Statements:H315-H319-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 1290634-35-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1290634-35-3 ]

[ 1290634-35-3 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 223671-15-6 ]
  • [ 74-88-4 ]
  • [ 1290634-35-3 ]
YieldReaction ConditionsOperation in experiment
88% With caesium carbonate; In N,N-dimethyl acetamide; at 50℃; for 3h; 7-Bromo-2-methylisoquinolin-1(2H)-one To a solution of 7-bromoisoquinolin- 1(2H)-one (500 mg, 2.23 mmol, 1.0 equiv) and Cs2CO3 (1.1 g, 3.35 mmol, 1.5 equiv) in DMA (10 m L) was added CH3I (475 mg, 3.35 mmol, 1.5 equiv) at rt. The mixture was stirred at 50 C for 3 hours. Upon completion, the reaction was cooled to rt and diluted with water (50 mL). The mixture was extracted with EtOAc (3 x 10 mL). The combined organic layers were washed with water (2 x 10 mL) and saturated brine (10 mL), and dried over anhydrous Na2SO4. The filtrate was concentrated under reduced pressure. The residue was purified by silica gel chromatography, eluting with EtOAc in PE (0~30%) to afford the title compound (470 mg, 88% yield) as a light yellow solid. 1H NMR (300 MHz, CDCl3) delta: 8.57 (d, J = 2.1 Hz, 1H), 7.70 (dd, J = 8.4 Hz, 2.1 Hz, 1H), 7.38 (d, J = 8.4 Hz, 1H), 7.08 (d, J = 7.2 Hz, 1H), 6.44 (d, J = 7.5 Hz, 1H), 3.60 (s, 3H). ESI-MS [M+H]+ calcd for (C10H8BrNOH+) 238.1, found 237.8, 239.8.
  • 2
  • [ 215453-51-3 ]
  • [ 1290634-35-3 ]
  • 3
  • [ 1290634-35-3 ]
  • [ 1313399-69-7 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 2 h / 80 °C / Inert atmosphere 2: palladium 10% on activated carbon; hydrogen / 12 h / 25 °C
Recommend Products
Same Skeleton Products
Historical Records