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Chemical Structure| 1306829-97-9 Chemical Structure| 1306829-97-9

Structure of 1306829-97-9

Chemical Structure| 1306829-97-9

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Product Details of [ 1306829-97-9 ]

CAS No. :1306829-97-9
Formula : C12H10N4S
M.W : 242.30
SMILES Code : CSC1=NC=C2C(NN=C2C3=CC=CC=C3)=N1

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Application In Synthesis of [ 1306829-97-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1306829-97-9 ]

[ 1306829-97-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1306829-95-7 ]
  • [ 98-80-6 ]
  • [ 1306829-97-9 ]
YieldReaction ConditionsOperation in experiment
87% With potassium phosphate;tetrakis(triphenylphosphine) palladium(0); In 1,4-dioxane; water; at 150℃; for 0.333333h;microwave irradiation; A microwave tube was charged with 3-bromo-6-(methylthio)-lH-pyrazolo[3,4- d]pyrimidine (1.0 g, 4.0 mmol), phenylboronic acid (1.5 g, 12 mmol), potassium phosphonate (2.5 g, 12 mmol), tetrakis(triphenylphosphine)palladium (0.35 g, 0,30 mmol), dioxane (16 mL) and water (4 mL) . The mixture was heated in microwave at 150 C for 20 min. The reaction mixture was poured into water. The aqueous layer was extracted with EtOAc (10X). The combined organic layer was dried (Na2S04), concentrated, and purified to provide 6- (methylthio)-3-phenyl-lH-pyrazolo[3,4-d]pyrimidme (0.85 g, 87%) as a white solid. MS m/z 243.1 [M+Hf.
 

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