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Chemical Structure| 132482-10-1 Chemical Structure| 132482-10-1

Structure of 132482-10-1

Chemical Structure| 132482-10-1

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Product Details of [ 132482-10-1 ]

CAS No. :132482-10-1
Formula : C11H21NO5S
M.W : 279.35
SMILES Code : O=C(N1[C@@H](COS(=O)(C)=O)CCC1)OC(C)(C)C
MDL No. :MFCD20272811

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Application In Synthesis of [ 132482-10-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 132482-10-1 ]

[ 132482-10-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 132482-10-1 ]
  • [ 137496-71-0 ]
YieldReaction ConditionsOperation in experiment
88% Slowly add lithium triethylborohydride (1M in THF, 17 mL, 17. mmol) to a 0 C solution of 2R-methanesulfonyloxymethyl-pyrrolidine-l-carboxylic acid tert-butyl ester (1.6 g, 5.73 mmol) in 10 mL of tetrahydrofuran. Warm the reaction mixture to ambient temperature and stir for 16 hours. Dilute the reaction mixture with ethyl acetate and water and wash successively with 0.1N HC1 and brine. Dry the crude organic extracts over MgS04, filter and concentrate to afford the title compound as a clear oil (0.930 g, 88%). 400 MHz NMR (CDC13) 8 3.83 (m, 1H), 3.38 (m, 2H), 1.92 (m, 3H), 1.58 (m, 1H), 1.48 (s, 9H), and 1.2 (d, J = 8 Hz, 3H).
 

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