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Chemical Structure| 13276-52-3 Chemical Structure| 13276-52-3
Chemical Structure| 13276-52-3

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Product Details of 2,6-Dichloropurine riboside

CAS No. :13276-52-3
Formula : C10H10Cl2N4O4
M.W : 321.12
SMILES Code : O[C@H]1[C@H](N2C=NC3=C(Cl)N=C(Cl)N=C23)O[C@H](CO)[C@H]1O
MDL No. :MFCD03411342
InChI Key :HJXWZGVMHDPCRS-UUOKFMHZSA-N
Pubchem ID :22791353

Safety of 2,6-Dichloropurine riboside

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 2,6-Dichloropurine riboside

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 13276-52-3 ]

[ 13276-52-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 94-98-4 ]
  • [ 13276-52-3 ]
  • [ 722527-50-6 ]
YieldReaction ConditionsOperation in experiment
84.9% With N-ethyl-N,N-diisopropylamine; In propan-1-ol; at 100℃; for 4h; EXAMPLE 1 2-Chloro-6-(2,4-dimethylbenzylamino)purine riboside <strong>[94-98-4]2,4-dimethylbenzylamine</strong> ( 8.35 g; 0.05 mol) was added to a suspension of 2,6-dichloropurine riboside (16.0 g; 0.05 mol) in n-propanol (100 niL) and N,N' ethyldiisopropylamine (6.44 g; 0.05 mol) was added. The reaction mixture was stirred at 100 C for 4 hours. After cooling to room temperature the precipitate was filtered off, washed with cold n-propanol (2x10 mL) and water (3x10 mL) and dried in the drying oven at 6O0C into constant weight. Yield: 6.26 g of yellowish substance (84.9%). TLC (chloroform-methanol; 85:15): one single spot; free of starting material, HPLC purity: 98+%
 

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