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Chemical Structure| 133091-81-3 Chemical Structure| 133091-81-3

Structure of 133091-81-3

Chemical Structure| 133091-81-3

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Product Details of [ 133091-81-3 ]

CAS No. :133091-81-3
Formula : C9H12N2
M.W : 148.21
SMILES Code : NC1CCC2=C(C1)N=CC=C2
MDL No. :MFCD12024793

Safety of [ 133091-81-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 133091-81-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 133091-81-3 ]

[ 133091-81-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 133091-81-3 ]
  • [ 156866-52-3 ]
  • [ 405058-77-7 ]
YieldReaction ConditionsOperation in experiment
100% With sodium borohydrid; In methanol; Preparation of {4-[(5,6,7,8-Tetrahydro-quinolin-7-ylamino)-methyl]-benzyl}-carbamic acid tert-butyl ester: Using general procedure B: Reaction of <strong>[156866-52-3](4-Formyl-benzyl)-carbamic acid tert-butyl ester</strong> (356 mg, 1.51 mmol), 5,6,7,8-Tetrahydro-quinolin-7-ylamine (224 mg, 1.51 mmol) in anhydrous MeOH (5 mL) at room temperature overnight under N2 and 2 min of stirring after addition of sodium borohydride (115 mg, 3.00 mmol), followed by purification of crude material using chromatography on silica gel (2:2:96 CH3OH-NH3 H2O-CH2Cl2) afforded the title compound (556 mg, 100percent) as a white foam.
 

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