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Chemical Structure| 133753-43-2 Chemical Structure| 133753-43-2

Structure of 133753-43-2

Chemical Structure| 133753-43-2

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Product Details of [ 133753-43-2 ]

CAS No. :133753-43-2
Formula : C12H7Br2N
M.W : 325.00
SMILES Code : BrC1=CC=CC2=C1C3=C(C=CC(Br)=C3)N2

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Application In Synthesis of [ 133753-43-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 133753-43-2 ]

[ 133753-43-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 890042-13-4 ]
  • 4,4,5,5-tetramethyl-2-(2-phenylnaphthyl-6-yl)-1,3,2-dioxaborolane [ No CAS ]
  • [ 133753-43-2 ]
  • 5-(6-phenylnaphthalen-2-yl)-3-(triphenylen-2-yl)-9H-carbazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
1) In a 500ml three-neck bottle,Add 3,5-dibromo-9H-carbazole (32.5 g, 100 mmol),Benzophenanthryl-2-borate (35.43 g, 100 mmol),Potassium carbonate (27.64 g, 200 mmol), 150 g of toluene, 75 g of ethanol,75 g of water, adding tetrakis(triphenylphosphine)palladium under N2 protection,After reacting at 85 C for 12 h, the reaction was completed by TLC and the temperature was lowered.After the temperature was lowered to room temperature, 6-phenylnaphthyl-1-borate (33.02 g, 100 mmol) was added to a three-necked flask, and the mixture was reacted at 85 C for 12 hours, and the reaction was confirmed by TLC.After cooling to room temperature, the reaction solution was washed twice with water (200 ml).The organic phase is obtained by liquid separation, decolorized by adding activated carbon, and filtered.The solvent was distilled off under reduced pressure, and then recrystallized twice with ethyl acetate.Drying under vacuum gave the intermediate 5-(6-phenylnaphthalen-2-yl)-3-(benzophenan-2-yl)-9H-indazole.
 

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