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Chemical Structure| 134521-16-7 Chemical Structure| 134521-16-7
Chemical Structure| 134521-16-7

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Synonyms: CGP 44 645

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Product Details of 4,4'-Dicyanobenzhydrol

CAS No. :134521-16-7
Formula : C15H10N2O
M.W : 234.25
SMILES Code : OC(C1=CC=C(C#N)C=C1)C2=CC=C(C#N)C=C2
Synonyms :
CGP 44 645
MDL No. :MFCD07367966
InChI Key :JNJWXPZHWUOYRZ-UHFFFAOYSA-N
Pubchem ID :10466550

Safety of 4,4'-Dicyanobenzhydrol

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 4,4'-Dicyanobenzhydrol

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 134521-16-7 ]
  • Downstream synthetic route of [ 134521-16-7 ]

[ 134521-16-7 ] Synthesis Path-Upstream   1~2

  • 1
  • [ 134521-16-7 ]
  • [ 32446-66-5 ]
YieldReaction ConditionsOperation in experiment
85% With manganese(IV) oxide In chloroform at 20℃; for 5.5 h; 4-[(4-Cyanophenyl)carbonylJbenzonitrile (6u). A suspension of 4-[(4- cyanophenyl)(hydroxy)methyl]benzonitrile (lOu) (0.68 g, 2.9 mmol), CHC13 (25 ml) and Mn02 (1.7 g, 17.4 mmol) was stirred for 1 h at it. Mn02 (0.8 g, 8.7 mmol) was added again and the suspension was stirred for 1.5 h at it. The suspension was filtered and to the yellowsolution Mn02 (1.7 g, 17.4 mmol) was added and stirred for 2 h again. After a new addition of Mn02 (0.3 g, 2.9 mmol) and stirring for 1 h the starting material was totally consumed. The Mn02 was filtered off and the filtrate was concentrated at reduced pressure to afford a pale yellow solid 6u (0.57 g, 85percent).
References: [1] Patent: WO2015/189265, 2015, A1, . Location in patent: Page/Page column 122.
  • 2
  • [ 105-07-7 ]
  • [ 32446-66-5 ]
  • [ 134521-16-7 ]
  • [ 100-47-0 ]
References: [1] Angewandte Chemie - International Edition, 2014, vol. 53, # 43, p. 11557 - 11561[2] Angew. Chem., 2016, vol. 126, # 43, p. 11741 - 11745,5.
 

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