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Chemical Structure| 135048-32-7 Chemical Structure| 135048-32-7

Structure of 135048-32-7

Chemical Structure| 135048-32-7

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Product Details of [ 135048-32-7 ]

CAS No. :135048-32-7
Formula : C7H6N4O
M.W : 162.15
SMILES Code : O=C(NN)C1=CC=NC(C#N)=C1
MDL No. :MFCD23132274
InChI Key :PPDYFTPCRSZNRD-UHFFFAOYSA-N
Pubchem ID :45084626

Safety of [ 135048-32-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 135048-32-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 135048-32-7 ]

[ 135048-32-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 29181-50-8 ]
  • [ 135048-32-7 ]
  • C14H9N7O [ No CAS ]
  • 2
  • [ 58481-14-4 ]
  • [ 135048-32-7 ]
YieldReaction ConditionsOperation in experiment
97% With hydrazine hydrochloride; In methanol; at 20 - 25℃; for 3.0h; To a 250 mL three-necked flask, add 130 mL of methanol,Ethyl 2-cyanoisonicotinate (30.0 g, 0.17 mol), stirred at room temperature,Add hydrazine monohydrochloride (13.0g, 0.19mol) in one portion at room temperature.Stir at 25 C for 3 hours, transfer to ice-water bath,Temperature control 0 5 ,150.0mL of water was added dropwise, 3% potassium hydroxide solution was added dropwise, and the temperature was controlled at 0 to 5 C.PH value is 7 8,Heat and stir for 3 hours, suction filter under reduced pressure, beat with 60.0mL water,Vacuum filtration,Dry in a 45 C vacuum drying oven,26.7g of 2-cyanoisoniazid (I) is obtained,Yellow solid, yield: 97.0%, HPLC: 99.2%.
 

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Related Functional Groups of
[ 135048-32-7 ]

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Related Parent Nucleus of
[ 135048-32-7 ]

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